SNCA gene

Known as: NACP, alpha synuclein gene, NON-A4 COMPONENT OF AMYLOID, PRECURSOR OF 
This gene plays a role in neuronal signaling.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Cells respond to stimuli by changes in various processes, including signaling pathways and gene expression. Efforts to identify… (More)
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Highly Cited
2007
Highly Cited
2007
Stem cells have been widely assumed to be capable of replacing lost or damaged cells in a number of diseases, including Parkinson… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT Identification and replication of susceptibility genes for Parkinson disease at the population level have been hampered… (More)
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Highly Cited
2005
Highly Cited
2005
Parkinson's disease (PD) is a disorder of movement, cognition, and emotion, and it is characterized pathologically by neuronal… (More)
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Highly Cited
2004
Highly Cited
2004
Aberrant alpha-synuclein degradation is implicated in Parkinson's disease pathogenesis because the protein accumulates in the… (More)
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Highly Cited
2004
Highly Cited
2004
Molecular chaperones, ubiquitin ligases and proteasome impairment have been implicated in several neurodegenerative diseases… (More)
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Highly Cited
2004
Highly Cited
2004
Lewy bodies (LBs), which are the hallmark pathologic features of Parkinson's disease and of dementia with LBs, have several… (More)
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Highly Cited
2003
Highly Cited
2003
Loss-of-function mutations in parkin are the major cause of early-onset familial Parkinson's disease. To investigate the… (More)
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Highly Cited
2003
Highly Cited
2003
Genome-wide screens were performed in yeast to identify genes that enhance the toxicity of a mutant huntingtin fragment or of… (More)
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Highly Cited
1997
Highly Cited
1997
Parkinson's disease (PD) is a common neurodegenerative disorder with a lifetime incidence of approximately 2 percent. A pattern… (More)
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