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SNCA gene

Known as: NACP, alpha synuclein gene, NON-A4 COMPONENT OF AMYLOID, PRECURSOR OF 
This gene plays a role in neuronal signaling.
National Institutes of Health

Related topics

Related topics

12 relations
Alzheimer's DiseaseApoptosisGene ExpressionHomo sapiens

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SNCA wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Proteomics of Caenorhabditis elegans over-expressing human alpha-synuclein analyzed by fluorogenic derivatization-liquid chromatography/tandem mass spectrometry: identification of actin and several…
It has been known that the over-expression of alpha-synuclein, the main protein of Lewy bodies in Parkinson's disease (PD), leads… 
Highly Cited
2007
Highly Cited
2007
Unsupervised Fluorescence Lifetime Imaging Microscopy for High Content and High Throughput Screening *S
Proteomics and cellomics clearly benefit from the molecular insights in cellular biochemical events that can be obtained by… 
2007
2007
Ansa [1]trochrocenophanes and their related unstrained 1,1'-disubstituted counterparts: synthesis and electronic structure.
The heteroleptic sandwich complex [Cr(eta(5)-C5H5)(eta(7)-C7H7)] (trochrocene) was prepared by subsequent treatment of CrCl3 with… 
2007
2007
Observation of multiple intermediates in alpha-synuclein fibril formation by singular value decomposition analysis.
2004
2004
Rapid self-assembly of alpha-synuclein observed by in situ atomic force microscopy.
Self-assembly of alpha-synuclein resulting in protein aggregates of diverse morphology has been implicated in the pathogenesis of… 
2003
2003
Identification and characterization of a novel Pyk2/related adhesion focal tyrosine kinase-associated protein that inhibits alpha-synuclein phosphorylation.
alpha-Synuclein is a presynaptic protein involved in the pathogenesis of several neurodegenerative diseases, such as Parkinson's… 
Review
2000
Review
2000
Polymorphisms of the Parkin Gene in Sporadic Parkinson’s Disease among Chinese in Taiwan
The role of genetics in Parkinson’s disease (PD), previously controversial, is now documented by several studies. A major… 
1999
1999
Search for the PARK3 founder haplotype in a large cohort of patients with Parkinson's disease from Northern Germany
A founder haplotype on chromosome 2p for autosomal dominant Parkinson's disease (PD) has been postulated for two families of… 
1998
1998
The alpha-synuclein Ala53Thr mutation is not a common cause of familial Parkinson's disease: a study of 230 European cases. European Consortium on Genetic Susceptibility in Parkinson's Disease.
We report the results of a screen of 230 European familial index cases of Parkinson's disease for the recently described Ala53Thr… 
1998
1998
Mutation screening in exons 3 and 4 of alpha-synuclein in sporadic Parkinson's and sporadic and familial dementia with Lewy bodies cases.
Recently it has been reported that a missense G(88)C mutation within exon 3 and a missense G(209)A mutation within exon 4 of the… 
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