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SMYD3 wt Allele

Known as: FLJ21080, ZMYND1, SET and MYND Domain Containing 3 wt Allele 
Human SMYD3 wild-type allele is located in the vicinity of 1q44 and is approximately 758 kb in length. This allele, which encodes SET and MYND domain… 
National Institutes of Health

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1q44Cell ProliferationMethylationSMYD3 protein, human

Broader (1)

SMYD3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Novel karyotypes of partial monosomy 21 and partial monosomy 1 and underlying etiology.
We report two novel karyotypes in the siblings of a Chinese family, 45,XY,der(1)t(1;21)(q44;q21)mat,-21 and 45,XX,der(1)t(1;21… 
2016
2016
Novel insights into the oncogenic function of the SMYD3 lysine methyltransferase.
SMYD3 is a member of the SMYD family of lysine methyltransferases (KMTs). In humans, there are five SMYD members (SMYD1–5) that… 
2016
2016
Mechanism of gene-specificity of oncogenic regulators
The generation of cancer-specific gene expression patterns is attributed to aberrant activation of oncogenic transcription… 
2016
2016
SMYD3 Is an Oncogene Required for Liver and Colon Tumorigenesis.
Nuclear SMYD3 promotes transcription of cancer-promoting genes includingJak1/2,Myc, andCtnnb1. 
Highly Cited
2012
Highly Cited
2012
Epigenetic regulation of miR‐124 by Hepatitis C Virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3
2012
2012
Tumor and Stem Cell Biology SMYD 3 Promotes Cancer Invasion by Epigenetic Upregulation of the Metalloproteinase MMP-9
Upregulation of the matrix metalloproteinase (MMP)–9 plays a central role in tumor progression and metastasis by stimulating cell… 
Highly Cited
2008
Highly Cited
2008
Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells
Histone methylation is involved in the regulation of gene expression and DNA replication through alteration of chromatin… 
2008
2008
Characterization and functional analysis of two novel genes, TIPUH1 and SMYD3, involved in human carcinogenesis
2007
2007
SMYD3 tandem repeats polymorphism is not associated with the occurrence and metastasis of hepatocellular carcinoma in a Chinese population.
UNLABELLED A variable number of tandem repeats (VNTR) polymorphism in regulatory region of SMYD3 coding for histone… 
2006
2006
[Experimental research of therapeutic effect on hepatocellular carcinoma of targeting SMYD3 gene inhibition by RNA interference].
OBJECTIVE To determine the potential of SMYD3 as a therapeutic target for hepatocellular carcinoma (HCC) by potent and highly… 
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