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SMAD7 gene

Known as: SMAD7, MOTHERS AGAINST DECAPENTAPLEGIC, DROSOPHILA, HOMOLOG OF, 7, SMAD family member 7 
This gene plays a role in signal transduction and regulation of transcription.
National Institutes of Health

Related topics

Related topics

3 relations
Signal TransductionSmad7 proteinprotein protein interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Circular RNA circ-SMAD7 promoted ovarian cancer cell proliferation and metastasis by suppressing KLF6.
OBJECTIVE Recently, the roles of circular RNAs (circRNAs) in tumor progression have attracted much attention. Currently, circ… 
2017
2017
Forkhead Box Protein 1 (FoxO1) Inhibits Accelerated β Cell Aging in Pancreas-specific SMAD7 Mutant Mice*
The mechanisms underlying the effects of exocrine dysfunction on the development of diabetes remain largely unknown. Here we show… 
2016
2016
TGF-β signaling is activated in patients with chronic HBV infection and repressed by SMAD7 overexpression after successful antiviral treatment
Although animal studies demonstrated that Smad7 induction ameliorates TGF-β/SMAD-mediated fibrogenesis, its role in human hepatic… 
Highly Cited
2016
Highly Cited
2016
MiR-424-5p participates in esophageal squamous cell carcinoma invasion and metastasis via SMAD7 pathway mediated EMT
AbstractBackgroundsESCC is a life-threatening disease due to invasion and metastasis in the early stage. Great efforts had been… 
2016
2016
Evaluation of breviscapine on prevention of experimentally induced abdominal adhesions in rats.
Highly Cited
2015
Highly Cited
2015
MiR-185-3p and miR-324-3p Predict Radiosensitivity of Nasopharyngeal Carcinoma and Modulate Cancer Cell Growth and Apoptosis by Targeting SMAD7
Background MiR-185-3p and miR-324-3p are 2 miRNAs that regulate nasopharyngeal carcinoma (NPC) radioresistance. This study tried… 
Highly Cited
2014
Highly Cited
2014
MicroRNA-92a Inhibition Attenuates Hypoxia/Reoxygenation-Induced Myocardiocyte Apoptosis by Targeting Smad7
Background MicroRNAs (miRNAs) regulate a lot of physiological and pathological processes, including myocardial ischemia… 
2008
2008
Structure–function relationship of inhibitory Smads: Structural flexibility contributes to functional divergence
Smads are a small family of eukaryotic transcription regulators that play key roles in the transforming growth factor‐beta… 
2002
2002
Phosphorylation regulation of the interaction between Smad7 and activin type I receptor
2001
2001
Combined copy status of 18q21 genes in colorectal cancer shows frequent retention of SMAD7
Deletions of chromosome band 18q21 appear with very high frequency in a variety of carcinomas, especially in colorectal cancer… 
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