SMAD7 gene

Known as: SMAD7, MOTHERS AGAINST DECAPENTAPLEGIC, DROSOPHILA, HOMOLOG OF, 7, SMAD family member 7 
This gene plays a role in signal transduction and regulation of transcription.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Crohn's disease-related inflammation is characterized by reduced activity of the immunosuppressive cytokine… (More)
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2015
2015
The cytokine transforming growth factor (TGF)-β1 plays a central role in diabetic nephropathy (DN) with data implicating the… (More)
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Highly Cited
2013
Highly Cited
2013
UNLABELLED Tumor recurrence and metastases are the major obstacles to improving the prognosis of patients with hepatocellular… (More)
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Highly Cited
2010
Highly Cited
2010
Hepcidin is the master regulatory hormone of systemic iron metabolism. Hepcidin deficiency causes common iron overload syndromes… (More)
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Highly Cited
2009
Highly Cited
2009
Leukemia inhibitory factor (LIF) activates the transcription factor signal transducer and activator of transcription 3 (STAT3… (More)
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Highly Cited
2007
Highly Cited
2007
To identify risk variants for colorectal cancer (CRC), we conducted a genome-wide association study, genotyping 550,163 tag SNPs… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS Defective transforming growth factor (TGF)-beta1 signaling due to high levels of Smad7 is a feature of… (More)
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2003
2003
Chromosomal region 18q21 is frequently deleted in colorectal cancer (CRC) and is associated with poor prognosis. Potential tumor… (More)
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Highly Cited
1999
Highly Cited
1999
Smad6 and Smad7 prevent ligand-induced activation of signal-transducing Smad proteins in the transforming growth factor-beta… (More)
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Highly Cited
1997
Highly Cited
1997
TGF-beta signals from the membrane to the nucleus through serine/threonine kinase receptors and their downstream effectors… (More)
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