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SMAD2 gene

Known as: SMAD family member 2, SMAD2, MOTHERS AGAINST DECAPENTAPLEGIC, DROSOPHILA, HOMOLOG OF, 2 
This gene plays a role in signal transduction and repression of transcription.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Activation of the canonical TGF-β signaling pathway provides growth inhibitory signals in the normal intestinal epithelium… Expand
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Highly Cited
2013
Highly Cited
2013
Human embryonic stem cells and mouse epiblast stem cells represent a primed pluripotent stem cell state that requires TGF… Expand
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Highly Cited
2010
Highly Cited
2010
Smad2 and Smad3 interact and mediate TGF-beta signaling. Although Smad3 promotes fibrosis, the role of Smad2 in fibrogenesis is… Expand
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Highly Cited
2010
Highly Cited
2010
Although it has been well established that TGF-beta plays a pivotal role in immune regulation, the roles of its downstream… Expand
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Highly Cited
2009
Highly Cited
2009
Loss of muscle mass occurs in a variety of diseases, including cancer, chronic heart failure, aquired immunodeficiency syndrome… Expand
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Review
2007
Review
2007
Transforming growth factor-beta (TGF-beta) is an important growth inhibitor of epithelial cells, and insensitivity to this… Expand
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Highly Cited
2002
Highly Cited
2002
The transcription factor Smad2 is released from cytoplasmic retention by TGFbeta receptor-mediated phosphorylation, accumulating… Expand
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Highly Cited
2002
Highly Cited
2002
Components of the transforming growth factor-beta and mitogen-activated protein kinase pathways interact in controlling cell… Expand
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Review
1997
Review
1997
Colorectal cancer is a significant cause of morbidity and mortality in Western populations. This cancer develops as a result of… Expand
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Highly Cited
1996
Highly Cited
1996
MAD-related (MADR) proteins are essential intracellular components of TGFbeta signaling pathways and are regulated by… Expand
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