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SMAD2 gene

Known as: SMAD family member 2, SMAD2, MOTHERS AGAINST DECAPENTAPLEGIC, DROSOPHILA, HOMOLOG OF, 2 
This gene plays a role in signal transduction and repression of transcription.
National Institutes of Health

Related topics

Related topics

9 relations
Cell Differentiation processCell Proliferation Regulatory ProcessColorectal CarcinomaHomo sapiens

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SMAD2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
miR-18b inhibits TGF-β1-induced differentiation of hair follicle stem cells into smooth muscle cells by targeting SMAD2.
2012
2012
Smad2 Decelerates Re-epithelialization during Gingival Wound Healing
During periodontal regeneration, inhibition of gingival downgrowth is necessary to promote migration of mesenchymal cells into… 
2012
2012
Examination of Smad2 and Smad4 copy-number variations in skin cancers
BackgroundSmad2 and Smad4 transcription factors were identified as the signalling mediators of transforming growth factor β (TGF… 
Highly Cited
2011
Highly Cited
2011
Global Identification of SMAD2 Target Genes Reveals a Role for Multiple Co-regulatory Factors in Zebrafish Early Gastrulas
Nodal and Smad2/3 signals play pivotal roles in mesendoderm induction and axis determination during late blastulation and early… 
Highly Cited
2003
Highly Cited
2003
Differential regulation of TGF-β signaling through Smad2, Smad3 and Smad4
Smad transcription factors mediate the growth inhibitory effect of transforming growth factor-β (TGF-β) in many cell types… 
2000
2000
Mutations of the Smad2 and Smad4 genes in lung adenocarcinomas induced by N‐nitrosobis(2‐hydroxypropyl)amine in rats
Mutations of the Smad2 and Smad4 genes, identified as mediators of the transforming growth factor‐β pathway, were investigated in… 
1998
1998
Mutation analysis of the Smad2 gene in human colon cancers using genomic DNA and intron primers.
In mammals, one of the Mad homologues, Smad2, was reported to be a mediator of TGF-beta signaling, and was found mutated in some… 
1998
1998
DPC4 splice variants in neuroblastoma.
Highly Cited
1997
Highly Cited
1997
Evidence that loss of chromosome 18q is associated with tumor progression.
Four sets of cell lines (UM-SCC-14A, -14B, and -14C; UM-SCC-17A and -17B; UM-SCC-81A and -81B; and UM-SCC-83A and -83B… 
1997
1997
Smad4 (homolog of human DPC4) and Smad2 (homolog of human JV18-1): candidates for murine lung tumor resistance and suppressor genes.
In this study we investigated the mouse mad-related genes, Smad4/Dpc4 and Smad2 (homolog of JV18-1), as candidates for… 
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