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SLIT3 gene

Known as: Slit Guidance Ligand 3 Gene, Slit-3, MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS 5 
This gene plays a role in the regulation of cell migration.
National Institutes of Health

Related topics

Related topics

9 relations
Angiogenic ProcessMigration, CellNeurogenesisSLIT1 gene
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Papers overview

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2018
2018
Osteoclast-secreted SLIT3 coordinates bone resorption and formation
Coupling is the process that links bone resorption to bone formation in a temporally and spatially coordinated manner within the… Expand
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2018
2018
Osteoclast-derived SLIT3 is a coupling factor linking bone resorption to bone formation
We identified osteoclast-derived SLIT3 as a new coupling factor using fractionated secretomics. Coupling links bone resorption to… Expand
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2018
2018
Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway
BackgroundIt is essential to understand the mechanisms responsible for hepatocellular carcinoma (HCC) progression and… Expand
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2017
2017
Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity
Rationale: Idiopathic or heritable pulmonary arterial hypertension is characterized by loss and obliteration of lung vasculature… Expand
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2017
2017
Recombinant Slit2 Reduces Surgical Brain Injury Induced Blood Brain Barrier Disruption via Robo4 Dependent Rac1 Activation in a Rodent Model
Brain tissue surrounding surgical resection site can be injured inadvertently due to procedures such as incision, retractor… Expand
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2015
2015
Mutations of the SLIT2–ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract
Congenital anomalies of the kidney and urinary tract (CAKUT) account for 40–50 % of chronic kidney disease that manifests in the… Expand
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Review
2009
Review
2009
Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics
Axon-guidance-pathway molecules are involved in connectivity and repair throughout life (beyond guiding brain wiring during fetal… Expand
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2004
2004
Genetic structure adds power to detect schizophrenia susceptibility at SLIT3 in the Chinese Han population.
The Chinese Han population, the largest population in the world, has traditionally been geographically divided into two parts… Expand
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Highly Cited
2001
Highly Cited
2001
Expression of slit-2 and slit-3 during chick development.
The Drosophila and vertebrate slit proteins have been characterized as secreted chemorepellents recognized by the robo receptor… Expand
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Highly Cited
1998
Highly Cited
1998
Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.
In Drosophila embryogenesis, the slit gene has been shown to play a critical role in CNS midline formation. However, no slit… Expand
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