SLCO1B1 wt Allele

Known as: OATP-C, OATP2, LST1 
Human SLCO1B1 wild-type allele is located in the vicinity of 12p12 and is approximately 109 kb in length. This allele, which encodes solute carrier… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Rosuvastatin is an HMG-CoA reductase inhibitor and one of the most hydrophilic among the commercially available statins. It is… (More)
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Highly Cited
2007
Highly Cited
2007
The elimination process of the endothelin receptor antagonist bosentan (Tracleer) in humans is entirely dependent on metabolism… (More)
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Highly Cited
2005
Highly Cited
2005
Microcystins are toxins produced by freshwater cyanobacteria. They are cyclic heptapeptides that exhibit hepato- and… (More)
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Highly Cited
2004
Highly Cited
2004
Pitavastatin, a novel potent 3-hydroxymethylglutaryl-CoA reductase inhibitor, is selectively distributed to the liver in rats… (More)
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Highly Cited
2003
Highly Cited
2003
Rifampin, a member of the rifamycin class of antibiotics, is well known for its ability to induce drug-metabolizing enzymes and… (More)
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Highly Cited
2002
Highly Cited
2002
Genetic polymorphisms of human organic anion transporting polypeptides OATP-C (SLC21A6) and OATP-B (SLC21A9) in the Japanese… (More)
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Highly Cited
2001
Highly Cited
2001
Bilirubin, the end product of heme catabolism, is taken up from the blood circulation into the liver. This work identifies a high… (More)
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Highly Cited
2000
Highly Cited
2000
We cloned and expressed a new organic anion transporting polypeptide (OATP), termed human OATP2, (OATP-C, LST-1; symbol SLC21A6… (More)
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Highly Cited
2000
Highly Cited
2000
Based on sequence homology to the human organic anion transporting polypeptide 2 (OATP2; SLC21A6), we cloned a new member of the… (More)
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Highly Cited
1999
Highly Cited
1999
We have isolated a novel liver-specific organic anion transporter, LST-1, that is expressed exclusively in the human, rat, and… (More)
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