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SLC7A7 gene

Known as: y+LAT-1, y(+)LAT1, SOLUTE CARRIER FAMILY 7 (CATIONIC AMINO ACID TRANSPORTER, y+ SYSTEM), MEMBER 7 
This gene plays a role in the transport of cationic amino acids.
National Institutes of Health

Related topics

Related topics

6 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Inducible Slc7a7 Knockout Mouse Model Recapitulates Lysinuric Protein Intolerance Disease
Lysinuric protein intolerance (LPI) is a rare autosomal disease caused by defective cationic amino acid (CAA) transport due to… 
2019
2019
y+LAT1 and y+LAT2 contribution to arginine uptake in different human cell models: Implications in the pathophysiology of Lysinuric Protein Intolerance
y+LAT1 (encoded by SLC7A7), together with y+LAT2 (encoded by SLC7A6), is the alternative light subunits composing the… 
2013
2013
Overexpression of SLC7A7 predicts poor progression-free and overall survival in patients with glioblastoma
The clinical significance of SLC7A7 expression remains unclear. In this study, we aimed to explore whether SLC7A7 expression in… 
2009
2009
Novel SLC7A7 large rearrangements in lysinuric protein intolerance patients involving the same AluY repeat
Lysinuric protein intolerance (LPI) is a rare autosomal inherited disease caused by defective cationic aminoacid transport 4F2hc… 
Highly Cited
2007
Highly Cited
2007
Regulation of renal amino acid transporters during metabolic acidosis.
The kidney plays a major role in acid-base homeostasis by adapting the excretion of acid equivalents to dietary intake and… 
2007
2007
Slc7a7 disruption causes fetal growth retardation by downregulating Igf1 in the mouse model of lysinuric protein intolerance.
The solute carrier family 7A member 7 gene (SLC7A7) encodes the light chain of the heterodimeric carrier responsible for cationic… 
2002
2002
Five novel SLC7A7 variants and y+L gene‐expression pattern in cultured lymphoblasts from Japanese patients with lysinuric protein intolerance
Two distinct human light subunits of the heteromeric amino acid transporter, y+LAT‐1 coded by SLC7A7 and y+LAT‐2 coded by SLC7A6… 
Review
2001
Review
2001
Recent molecular advances in mammalian glutamine transport.
Much has been learned about plasma membrane glutamine transporter activities in health and disease over the past 30 years… 
Review
2000
Review
2000
SLC7A7 genomic structure and novel variants in three Japanese lysinuric protein intolerance families
Lysinuric protein intolerance (LPI) is a rare inherited disease caused by defective transport of the dibasic amino acids at the… 
Highly Cited
1999
Highly Cited
1999
SLC7A7, encoding a putative permease-related protein, is mutated in patients with lysinuric protein intolerance
Lysinuric protein intolerance (LPI, MIM 222700) is an autosomal recessive multisystem disorder found mainly in Finland and Italy… 
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