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SLC7A6 protein, human
Known as:
Cationic Amino Acid Transporter, y+ System
, LAT3 protein, human
, Solute Carrier Family 7 Member 6
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Y+L amino acid transporter 2 (515 aa, ~57 kDa) is encoded by the human SLC7A6 gene. This protein is involved in dibasic amino acid transport.
National Institutes of Health
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Related topics
Related topics
13 relations
Broader (1)
Amino Acid Transport Systems, Basic
Amino Acid Transporter
Cellular Membrane
Integral Membrane Proteins
Ionophore activity
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The Glutamine Transporters and Their Role in the Glutamate/GABA-Glutamine Cycle.
R. Leke
,
A. Schousboe
Advances in neurobiology
2016
Corpus ID: 38181176
Glutamine is a key amino acid in the CNS, playing an important role in the glutamate/GABA-glutamine cycle (GGC). In the GGC…
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Review
2015
Review
2015
Maternal Factors Are Associated with the Expression of Placental Genes Involved in Amino Acid Metabolism and Transport
P. Day
,
G. Ntani
,
+8 authors
J. Cleal
PloS one
2015
Corpus ID: 4852506
Introduction Maternal environment and lifestyle factors may modify placental function to match the mother’s capacity to support…
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Highly Cited
2013
Highly Cited
2013
Dietary arginine supplementation enhances intestinal expression of SLC7A7 and SLC7A1 and ameliorates growth depression in mycotoxin-challenged pigs
J. Yin
,
W. Ren
,
+5 authors
Guoyao Wu
Amino Acids
2013
Corpus ID: 12129737
This study tested the hypothesis that dietary l-arginine supplementation confers beneficial effects on growing pigs fed a mold…
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Highly Cited
2012
Highly Cited
2012
Upregulation of the heteromeric y+LAT2 transporter contributes to ammonia-induced increase of arginine uptake in rat cerebral cortical astrocytes
M. Zielińska
,
M. Skowrońska
,
I. Frȩśko
,
J. Albrecht
Neurochemistry International
2012
Corpus ID: 34044628
Highly Cited
2012
Highly Cited
2012
Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassing oxidative/nitrosative stress and activation of matrix metalloproteinases
M. Skowrońska
,
M. Zielińska
,
+4 authors
J. Albrecht
Journal of neurochemistry
2012
Corpus ID: 205624255
J. Neurochem. (2012) 121, 125–134.
Highly Cited
2007
Highly Cited
2007
Possible involvement of oxidative stress in piperonyl butoxide induced hepatocarcinogenesis in rats.
M. Muguruma
,
A. Unami
,
+6 authors
K. Mitsumori
Toxicology
2007
Corpus ID: 44477338
Highly Cited
2007
Highly Cited
2007
Identification of a Novel Polymorphism in the 3′UTR of the l-Arginine Transporter Gene SLC7A1: Contribution to Hypertension and Endothelial Dysfunction
Zhiyong Yang
,
K. Venardos
,
E. Jones
,
B. Morris
,
J. Chin-Dusting
,
D. Kaye
Circulation
2007
Corpus ID: 1616213
Background— Endothelial dysfunction because of reduced nitric oxide bioavailability is a key feature of essential hypertension…
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Highly Cited
2004
Highly Cited
2004
Characterization of cationic amino acid transporters and expression of endothelial nitric oxide synthase in human placental microvascular endothelial cells
J. Dye
,
S. Vause
,
+5 authors
J. Glazier
FASEB journal : official publication of the…
2004
Corpus ID: 14107989
We investigated the expression and activity of arginine transporters and endothelial nitric oxide synthase (eNOS) in human…
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Highly Cited
2001
Highly Cited
2001
Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains.
A. Bröer
,
B. Friedrich
,
+4 authors
S. Bröer
The Biochemical journal
2001
Corpus ID: 22158349
Heterodimeric amino acid transporters are comprised of a type-II membrane protein named the heavy chain (4F2hc or rBAT) that may…
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Highly Cited
2000
Highly Cited
2000
The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine.
A. Bröer
,
C. Wagner
,
F. Lang
,
S. Bröer
The Biochemical journal
2000
Corpus ID: 1378623
The cationic amino acid arginine, due to its positive charge, is usually accumulated in the cytosol. Nevertheless, arginine has…
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