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SLC6A1 gene

Known as: GABA transporter 1, GABA TRANSPORTER, GAT1 
National Institutes of Health

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GABA Transporter 1
GABA transporter

Papers overview

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Highly Cited
2009
Highly Cited
2009
Synaptic and extrasynaptic GABA transporters as targets for anti‐epileptic drugs
Inhibition of the GABA transporter subtype GAT1 by the clinically available anti‐epileptic drug tiagabine has proven to be an… 
Highly Cited
2009
Highly Cited
2009
The Yeast GATA Factor Gat1 Occupies a Central Position in Nitrogen Catabolite Repression-Sensitive Gene Activation
ABSTRACT Saccharomyces cerevisiae cells are able to adapt their metabolism according to the quality of the nitrogen sources… 
Highly Cited
2007
Highly Cited
2007
Control of Ammonium Permease Expression and Filamentous Growth by the GATA Transcription Factors GLN3 and GAT1 in Candida albicans
ABSTRACT In response to nitrogen starvation, the human fungal pathogen Candida albicans switches from yeast to filamentous growth… 
Highly Cited
2006
Highly Cited
2006
Differing responses of Gat1 and Gln3 phosphorylation and localization to rapamycin and methionine sulfoximine treatment in Saccharomyces cerevisiae.
Gln3 and Gat1/Nil1 are GATA-family transcription factors responsible for transcription of nitrogen-catabolic genes in… 
Review
2004
Review
2004
GABA transporters as drug targets for modulation of GABAergic activity.
2003
2003
Syntaxin 1A inhibits GABA flux, efflux, and exchange mediated by the rat brain GABA transporter GAT1.
GABA transporters control extracellular GABA levels by coupling transmitter uptake to the sodium and chloride cotransport. The… 
Highly Cited
2000
Highly Cited
2000
Role of Cl− in Electrogenic Na+-coupled Cotransporters GAT1 and SGLT1*
We have investigated the functional role of Cl− in the human Na+/Cl−/γ-aminobutyric acid (GABA) and Na+/glucose cotransporters… 
Highly Cited
1999
Highly Cited
1999
Inhibition of uptake, steady‐state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs
We have expressed the GABA transporter (GAT1) of mouse brain in Xenopus oocytes and have investigated the effects of four… 
Highly Cited
1997
Highly Cited
1997
Second Messengers, Trafficking-Related Proteins, and Amino Acid Residues that Contribute to the Functional Regulation of the Rat Brain GABA Transporter GAT1
Recent evidence indicates that several members of the Na+-coupled transporter family are regulated, and this regulation in part… 
Highly Cited
1996
Highly Cited
1996
Developmental Expression of GABA Transporters GAT1 and GAT4 Suggests Involvement in Brain Maturation
Abstract: cDNA clones representing four pharmacologically distinct GABA transporters (GAT1–GAT4) were previously identified in… 
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