SLC46A1 gene

Known as: PCFT, HEME CARRIER PROTEIN 1, MGC9564 
This gene plays a role in folate and antifolate transport.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
0102019952017

Papers overview

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2010
2010
Folates are essential vitamins that play a key role as one-carbon donors in a spectrum of biosynthetic pathways including RNA and… (More)
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2009
2009
Genetic disorders of homocysteine (Hcy) or folate metabolism or high-methionine diets elevate plasma Hcy and its atherogenic… (More)
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2008
2008
The proton-coupled folate transporter (PCFT/SLC46A1) displays optimal and prominent folate and antifolate transport activity at… (More)
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2008
2008
BACKGROUND Folate is an essential nutrient that supports nucleotide synthesis and biological methylation reactions. Diminished… (More)
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2008
2008
The human proton-coupled folate transporter (HsPCFT, SLC46A1) mediates intestinal absorption of folates and transport of folates… (More)
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2008
2008
Reduced derivatives of folic acid (folates) play a critical role in the development, function and repair of the CNS. However, the… (More)
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2008
2008
Proton-coupled folate transporter/heme carrier protein 1 (PCFT/HCP1) has recently been identified as a transporter that mediates… (More)
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2007
2007
BACKGROUND Folic acid [corrected] plays an essential role in cellular metabolism. Its deficiency can lead to neural tube defects… (More)
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2007
2007
This laboratory recently identified a human gene that encodes a novel folate transporter [Homo sapiens proton-coupled folate… (More)
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2007
2007
The functional characteristics of human proton coupled folate transporter (hPCFT)/heme carrier protein (HCP) 1 were investigated… (More)
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