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SLC45A2 wt Allele

Known as: 1A1, SHEP5, AIM1 
Human SLC45A2 wild-type allele is located in the vicinity of 5p13.2 and is approximately 40 kb in length. This allele, which encodes membrane… 
National Institutes of Health

Related topics

Related topics

6 relations
5p13.2Cell Differentiation processHomo sapiensLigand Binding

Papers overview

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Highly Cited
2008
Highly Cited
2008
SLC45A2: a novel malignant melanoma‐associated gene
Human pigmentation appears to be one of the strongest risk factors for malignant melanoma (MM). In humans, there is a long list… 
Highly Cited
2004
Highly Cited
2004
High Expression of Aurora-B/Aurora and Ipl1-Like Midbody-Associated Protein (AIM-1) in Astrocytomas
AbstractObjective: Impaired regulation of Aurora-B/AIM-1 expression in human cells causes chromosomal abnormality and instability… 
Highly Cited
2004
Highly Cited
2004
Monoamniotic twin pregnancies: antenatal management and perinatal results of 19 consecutive cases
Objective  To describe the obstetric management and perinatal outcome of antenatally diagnosed monoamniotic twin pregnancies… 
Highly Cited
2002
Highly Cited
2002
Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation.
The current study was designed to determine the mechanistic basis for differences in the effects of naturally occurring… 
Highly Cited
2001
Highly Cited
2001
Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin.
Recently we reported that resveratrol (trans-3,4',5-trihydroxystilbene) showed selective inhibition of recombinant human… 
Highly Cited
2000
Highly Cited
2000
Ultraviolet-B exposure of human skin induces cytochromes P450 1A1 and 1B1.
The cytochromes P450 belong to a multigene superfamily and are responsible for the metabolic activation of both xenobiotics and… 
Highly Cited
1999
Highly Cited
1999
Resveratrol is a selective human cytochrome P450 1A1 inhibitor.
Resveratrol (trans-3,4',5-trihydroxystilbene) is a phytoalexin compound found in juice and wine produced from dark-skinned grape… 
Highly Cited
1998
Highly Cited
1998
Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1.
While the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by N-hydroxylation has been well… 
Highly Cited
1994
Highly Cited
1994
ATP inhibits the hydrosmotic effect of AVP in rabbit CCT: evidence for a nucleotide P2u receptor.
In rabbit renal cortical collecting tubule (CCT), perfused in vitro at 38 degrees C, ATP in concentrations of 10(-7) M and… 
Highly Cited
1994
Highly Cited
1994
Expression of modified human cytochrome P450 1A1 in Escherichia coli: effects of 5' substitution, stabilization, purification, spectral characterization, and catalytic properties.
Human cytochrome P450 (P450) 1A1 is primarily an extrahepatic enzyme and is important because of its roles in the activation of… 
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