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SLC31A2 gene

Known as: SOLUTE CARRIER FAMILY 31 (COPPER TRANSPORTER), MEMBER 2, hCTR2, solute carrier family 31 member 2 
 
National Institutes of Health

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SLC31A1 gene

Papers overview

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Highly Cited
2013
Highly Cited
2013
The Arabidopsis COPT6 transport protein functions in copper distribution under copper-deficient conditions.
Copper (Cu), an essential redox active cofactor, participates in fundamental biological processes, but it becomes highly… Expand
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Highly Cited
2013
Highly Cited
2013
Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain
Significance Copper is essential for normal growth and development because it serves roles in catalysis, signaling, and structure… Expand
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Highly Cited
2013
Highly Cited
2013
Arabidopsis Copper Transport Protein COPT2 Participates in the Cross Talk between Iron Deficiency Responses and Low-Phosphate Signaling1[C][W]
A copper transport protein affects copper, iron, and phosphate deficiency responses. Copper and iron are essential micronutrients… Expand
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Review
2012
Review
2012
Membrane Transporters as Mediators of Cisplatin Effects and Side Effects
Transporters are important mediators of specific cellular uptake and thus, not only for effects, but also for side effects… Expand
Highly Cited
2011
Highly Cited
2011
Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice
BackgroundThe copper (Cu) transporter (COPT/Ctr) gene family has an important role in the maintenance of Cu homeostasis in… Expand
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Highly Cited
2010
Highly Cited
2010
Gene expression profiling analysis of copper homeostasis in Arabidopsis thaliana.
As a result of copper essentiality for life, plants and most other organisms have developed a conserved and complex network of… Expand
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Highly Cited
2009
Highly Cited
2009
Copper Transporter 2 Regulates the Cellular Accumulation and Cytotoxicity of Cisplatin and Carboplatin
Purpose: Copper transporter 2 (CTR2) is known to mediate the uptake of Cu+1 by mammalian cells. Several other Cu transporters… Expand
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Highly Cited
2008
Highly Cited
2008
Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells.
Ctr1 (copper transporter 1) mediates high-affinity copper uptake. Ctr2 (copper transporter 2) shares sequence similarity with… Expand
Highly Cited
2007
Highly Cited
2007
Identification of a Vacuole-associated Metalloreductase and Its Role in Ctr2-mediated Intracellular Copper Mobilization*
Copper is an essential trace metal whose biological utility is derived from its ability to cycle between oxidized Cu(II) and… Expand
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Highly Cited
2004
Highly Cited
2004
Mobilization of Intracellular Copper Stores by the Ctr2 Vacuolar Copper Transporter*
Copper plays an essential role in processes including signaling to the transcription and protein trafficking machinery, oxidative… Expand
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