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SLC22A6 gene

Known as: ROAT1, SOLUTE CARRIER FAMILY 22 (ORGANIC ANION TRANSPORTER), MEMBER 6, solute carrier family 22 member 6 
National Institutes of Health

Related topics

Related topics

1 relation
Organic Anion Transport Protein 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Organic anion transporter OAT1 is involved in renal handling of citrulline.
Because citrulline plasma concentration is elevated in kidney failure, citrulline could be a biomarker of renal insufficiency… 
2008
2008
Time Course of Organic Anion Excretion in Rats with Bilateral Ureteral Obstruction: Role of Organic Anion Transporters (Oat1 and Oat3)
Background: Urinary tract obstruction is a common cause of renal failure. In this study, we evaluated the time course of P… 
Highly Cited
2007
Highly Cited
2007
Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats.
Ischemic acute renal failure (iARF) was described to reduce renal extraction of the organic anion para-aminohippurate (PAH) in… 
2006
2006
Primary porcine proximal tubular cells as a model for transepithelial drug transport in human kidney.
Highly Cited
2005
Highly Cited
2005
Altered renal elimination of organic anions in rats with chronic renal failure.
Highly Cited
2005
Highly Cited
2005
Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1)
Objectives The organic anion transporter, OAT1 (SLC22A6), plays a role in the renal elimination of many drugs and environmental… 
2005
2005
Transport of N-Acetylcysteine S-Conjugates of Methylmercury in Madin-Darby Canine Kidney Cells Stably Transfected with Human Isoform of Organic Anion Transporter 1
Recent studies have implicated the activity of the organic anion transporter 1 (OAT1) protein in the basolateral uptake of… 
2005
2005
Handling of the Homocysteine S-Conjugate of Methylmercury by Renal Epithelial Cells: Role of Organic Anion Transporter 1 and Amino Acid Transporters
Recently, the activity of the organic anion transporter 1 (OAT1) protein has been implicated in the basolateral uptake of… 
2003
2003
Up-regulation of organic anion transporter 1 protein is induced by chronic furosemide or hydrochlorothiazide infusion in rat kidney.
BACKGROUND Thiazide and loop diuretics are secreted from the proximal tubule via the organic anion transport system to reach… 
2002
2002
Rat renal organic anion transporter rOAT1 mediates transport of urinary-excreted cephalosporins, but not of biliary-excreted cefoperazone.
Most cephalosporin antibiotics are excreted into urine via glomerular filtration and active tubular secretion by renal organic… 
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