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SLC22A5 gene
Known as:
solute carrier family 22 member 5
, SCD
, SLC22A5
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National Institutes of Health
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Related topics
Related topics
2 relations
Renal carnitine transport defect
SLC22A2 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Up-regulation of hepatic fatty acid transporters and inhibition/down-regulation of hepatic OCTN2 contribute to olanzapine-induced liver steatosis.
Ting Jiang
,
Yingqiong Zhang
,
+7 authors
Huidi Jiang
Toxicology Letters
2019
Corpus ID: 201617396
2010
2010
Quantitative structure activity relationship for inhibition of human organic cation/carnitine transporter.
Lei Diao
,
S. Ekins
,
J. Polli
Molecular Pharmaceutics
2010
Corpus ID: 12165741
Organic cation/carnitine transporter (OCTN2; SLC22A5) is an important transporter for L-carnitine homeostasis, but can be…
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2010
2010
OCTN2 is associated with carnitine transport capacity of rat skeletal muscles
Y. Furuichi
,
Tomoko Sugiura
,
Yukio Kato
,
Y. Shimada
,
K. Masuda
Acta Physiologica
2010
Corpus ID: 21258913
Aim: Carnitine plays an essential role in fat oxidation in skeletal muscles; therefore carnitine influx could be crucial for…
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2008
2008
The inhibitory effects of fluoroquinolones on L-carnitine transport in placental cell line BeWo.
T. Hirano
,
S. Yasuda
,
+4 authors
K. Iseki
International journal of pharmaceutics
2008
Corpus ID: 22091808
2007
2007
OCTN2-mediated carnitine uptake in a newly discovered human proximal tubule cell line (Caki-1).
Natalie D. Glube
,
E. Closs
,
P. Langguth
Molecular Pharmaceutics
2007
Corpus ID: 10026802
The proximal tubular reabsorption of carnitine in the human kidney is significant because more than 95% of the carnitine filtered…
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2005
2005
SATURABLE DISTRIBUTION OF TACRINE INTO THE STRIATAL EXTRACELLULAR FLUID OF THE RAT: EVIDENCE OF INVOLVEMENT OF MULTIPLE ORGANIC CATION TRANSPORTERS IN THE TRANSPORT
Jong-Hyuk Sung
,
Kyung-Ha Yu
,
+4 authors
S. Chung
Drug Metabolism And Disposition
2005
Corpus ID: 9073298
The kinetics and mechanism by which tacrine is distributed in the rat brain were examined. Tacrine levels in plasma and striatal…
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2005
2005
Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells.
Daisuke Kobayashi
,
M. Irokawa
,
Tomoji Maeda
,
A. Tsuji
,
I. Tamai
Reproduction
2005
Corpus ID: 19669334
Carnitine is essential for the acquisition of motility and maturation of spermatozoa in the epididymis, and is accumulated in…
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2003
2003
Downregulation of carnitine acyltransferases and organic cation transporter OCTN2 in mononuclear cells in healthy elderly and patients with myelodysplastic syndromes
H. Karlic
,
A. Lohninger
,
+6 authors
M. Pfeilstöcker
Journal of molecular medicine
2003
Corpus ID: 10992930
Changes in key enzymes of oxidative metabolism at the mitochondrial level are known to be associated with the aging process…
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2003
2003
Functional Domains in the Carnitine Transporter OCTN2, Defective in Primary Carnitine Deficiency*
Cristina Amat di San Filippo
,
Yuhuan Wang
,
N. Longo
Journal of Biological Chemistry
2003
Corpus ID: 22447965
Primary carnitine deficiency is an autosomal recessive disorder of fatty acid oxidation characterized by hypoketotic hypoglycemia…
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2002
2002
Age-associated cardiomyopathy in heterozygous carrier mice of a pathological mutation of carnitine transporter gene, OCTN2.
E. Xiaofei
,
Y. Wada
,
+6 authors
A. Koizumi
The journals of gerontology. Series A, Biological…
2002
Corpus ID: 41083001
The purpose of this study was to test whether heterozygotes of juvenile visceral steatosis mice, a model for systemic carnitine…
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