SLC16A3 wt Allele

Known as: MCT-3, MCT-4, Solute Carrier Family 16 (Monocarboxylate Transporter), Member 3 wt Allele 
Human SLC16A3 wild-type allele is located in the vicinity of 17q25 and is approximately 33 kb in length. This allele, which encodes monocarboxylate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
We have recently proposed a new model of cancer metabolism to explain the role of aerobic glycolysis and L-lactate production in… (More)
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Highly Cited
2011
Highly Cited
2011
Monocarboxylate transporters (MCTs) are transmembrane proteins involved in the transport of monocarboxylates across the plasma… (More)
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Highly Cited
2011
Highly Cited
2011
Recently, we proposed a new mechanism for understanding the Warburg effect in cancer metabolism. In this new paradigm, cancer… (More)
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Highly Cited
2011
Highly Cited
2011
Malignant tumors exhibit increased dependence on glycolysis, resulting in abundant export of lactic acid, a hypothesized key step… (More)
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Highly Cited
2006
Highly Cited
2006
The monocarboxylate transporter MCT4 mediates lactic acid efflux from most tissues that are dependent on glycolysis for their ATP… (More)
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Review
2001
Review
2001
It is now known that lactate traverses the plasma membrane of many tissues, including heart and muscle, via a stereo-specific, pH… (More)
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Highly Cited
2000
Highly Cited
2000
CD147 is a broadly expressed plasma membrane glycoprotein containing two immunoglobulin-like domains and a single charge… (More)
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Highly Cited
2000
Highly Cited
2000
To evaluate the effects of endurance training on the expression of monocarboxylate transporters (MCT) in human vastus lateralis… (More)
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Review
2000
Review
2000
  • Arend Bonen
  • Medicine and science in sports and exercise
  • 2000
Lactate traverses the cell membranes of many tissues, including the heart and skeletal muscle via a facilitated monocarboxylate… (More)
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Review
1999
Review
1999
Skeletal muscle is the major producer of lactic acid in the body, but its oxidative fibres also use lactic acid as a respiratory… (More)
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