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SK-7041

 
National Institutes of Health

Papers overview

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2013
2013
PURPOSE This preclinical study is to determine whether the capacity of histone deacetylase (HDAC) inhibitors to enhance radiation… Expand
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Highly Cited
2009
Highly Cited
2009
Excessive accumulation of extracellular matrix (ECM) in the kidneys and epithelial-to-mesenchymal transition (EMT) of renal… Expand
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2008
2008
Activation of the JAK/STAT pathway appears common in AML, occurring in up to 70% of AML patients. Therefore, JAK/STAT signal… Expand
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2007
2007
Although STI571 still plays a key role in the treatment of chronic myeloid leukemia, emergence of resistance to STI571 is a major… Expand
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2007
2007
Histone acetyltransferase (HAT) and histone deacetylase (HDAC) activities determine the acetylation status of histones, which… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND A number of distinct stress signaling pathways in myocardium cause cardiac hypertrophy and heart failure. Class II… Expand
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2006
2006
BACKGROUND A class of synthetic histone deacetylase (HDAC) inhibitors, which are hybrids of trichostatin A and MS-275 were… Expand
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2006
2006
A novel hybrid synthetic histone deacetylase inhibitor, SK-7041, was synthesized from hydroaxamic acid of trichostatin A (TSA… Expand
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2005
2005
Histone acetyltransferase (HAT) and histone deacetylase (HDAC) activities determine the acetylation status of histones, and have… Expand
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Highly Cited
2004
Highly Cited
2004
We have developed previously a class of synthetic hybrid histone deacetylase (HDAC) inhibitors, which were built from hydroxamic… Expand
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