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SK&F 93479

Known as: 4(1H)-Pyrimidinone, 2-((2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)amino)-5-((6-methyl-3-pyridinyl)methyl)-, trihydrochloride, SK&F-93479, SKF 93479 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Histamine H2 AntagonistsPyrimidinones

Papers overview

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Review
1991
Review
1991
Neuroendocrine cell hyperplasia and neuroendocrine carcinoma of the rodent fundic stomach.
1989
1989
In vitro accumulation of thyroid hormones by cultured rat hepatocytes and the biliary excretion of iodothyronines in rats treated with a novel histamine H2-receptor antagonist.
1987
1987
Effects of toxic doses of a novel histamine (H2) antagonist on the rat thyroid gland.
1987
1987
Gastric neuroendocrine cell hyperplasia after treatment with the long-acting, potent H2-receptor antagonist SK&F 93479.
The time course and dose response of the neuroendocrine cell hyperplasia in the oxyntic mucosa of the rat was examined after… 
1986
1986
Pharmacology of histamine H2 receptor antagonists in the human gastric cancer cell line HGT-1. Structure-activity relationship of isocytosine-furan and imidazole derivatives related to cimetidine.
1986
1986
Pharmacological study of basal acid secretion by the rat isolated fundus preparation.
The rat isolated stomach preparation secretes acid in the absence of exogenous stimulants. This basal secretion of acid was… 
1985
1985
Selective disappearance of histamine H2-receptor activity in the human gastric cancer cell line HGT-1 after short-term or chronic treatment by histamine or its H2-antagonists
Homologous loss of histamine H2-receptor activity (cAMP generation) was observed after short-term (10–20 min) or chronic… 
1984
1984
Pathology of the forestomach in rats treated for 1 year with a new histamine H2-receptor antagonist, SK&F 93479 trihydrochloride.
: The new long acting histamine H2-receptor antagonist was administered to rats at doses of 1000, 200 and 40 mg/kg body weight… 
1984
1984
Effects of SK&F 93479 on experimentally induced ventricular arrhythmias in dogs, rats and mice
The effects of SK&F 93479, a potent histamine H2-receptor antagonist, on ventricular arrhythmias induced by coronary artery… 
1983
1983
Cardiac effects of the new H2-receptor antagonists
A series of new H2-receptor antagonists were tested for their effects on different isolated heart preparations. In the guinea-pig… 
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