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SK&F 88046

Known as: SK&F-88046, SKF 88046 
National Institutes of Health

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1 relation

Broader (1)

Sulfonamides

Papers overview

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1995
1995
Eicosanoid-mediated Cl− secretion induced by the antitumor drug, irinotecan (CPT-11), in the rat colon
Irinotecan (CPT-11) is active against a broad range of human cancer. One of the side-effects of irinotecan is a strong diarrhoea… 
1994
1994
Thromboxane-like actions of prostaglandin D2 on the contractility of the rat colon in vitro.
Prostaglandin D2 (PGD2) concentration-dependently induced a contraction of the longitudinal muscle of the intact isolated rat… 
1988
1988
Effects of the thromboxane receptor antagonist SK&F 88046 in the canine, monkey and human coronary vasculature.
1987
1987
Interference of the thromboxane antagonist SK&F 88046 with platelet activation and subsequent desensitization by arachidonic acid and the thromboxane mimetics U46619 and EP171.
1985
1985
SK&F 88046: inhibition of thromboxane-induced bronchoconstriction in anesthetized dogs.
In addition to its well-described pro-aggregatory action, thromboxane A2 (TxA2) has been shown to be a potent bronchoconstrictor… 
1984
1984
Antagonism of the Cardiac Effects of Leukotriene C4 by Compound SKF 88046: Dissociation of Effects on Contractility and Coronary Flow
In the present study, we evaluated the properties of an imidodisulfamide derivative, compound SKF 88046, as an antagonist of the… 
1984
1984
Identification of leukotriene D4 specific binding sites in the membrane preparation isolated from guinea pig lung.
1984
1984
Analysis of the antagonist profile of SK&F 88046 on guinea pig trachea.
1984
1984
Antagonism of the Cardiac Effects of Leukotriene C: Dissociation of Effects on Contractility and Coronary Flow4: Dissociation of Effects on Contractility and Coronary Flow by Compound Skf 88046…
In the present study, we evaluated the properties of an imidodisulfamide derivative, compound SKF 88046, as an antagonist of the… 
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