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SK&F 88046

Known as: SK&F-88046, SKF 88046 
 
National Institutes of Health

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1995
1995
Irinotecan (CPT-11) is active against a broad range of human cancer. One of the side-effects of irinotecan is a strong diarrhoea… Expand
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1994
1994
PGD2, the predominant prostanoid released from activated human lung mast cells, is metabolized to 9 alpha, 11 beta-PGF2 by an 11… Expand
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1989
1989
Prostaglandin D2 (PGD2), the major product of arachidonic acid metabolism via the cyclooxygenase pathway in most mast cells, is… Expand
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1988
1988
U-46619, a stable "functional" thromboxane/endoperoxide receptor agonist, produced potent contractile responses in isolated… Expand
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1985
1985
Strips of rabbit blood vessels were suspended in vitro and responses to complement peptides C3a and C5a were recorded… Expand
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1985
1985
Using [3H]leukotriene C4 (LTC4) and radioligand-binding techniques, specific leukotriene C4 binding sites have been identified in… Expand
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1984
1984
SK&F 88046, an imidodisulfamide initially reported as an end organ leukotriene (LT)D4 antagonist on guinea-pig lung parenchyma… Expand
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1984
1984
In the present study, we evaluated the properties of an imidodisulfamide derivative, compound SKF 88046, as an antagonist of the… Expand
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1984
1984
A radioligand binding assay has been established to study leukotriene specific binding sites in the guinea pig and rabbit tissues… Expand
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1984
1984
SK&F 88046 preferentially antagonized the contractions elicited by the functional thromboxane (Tx) A2 mimics and structural… Expand
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