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SK&F 88046

Known as: SK&F-88046, SKF 88046 
 
National Institutes of Health

Papers overview

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1994
1994
PGD2, the predominant prostanoid released from activated human lung mast cells, is metabolized to 9 alpha, 11 beta-PGF2 by an 11… Expand
Highly Cited
1989
Highly Cited
1989
Prostaglandin D2 (PGD2), the major product of arachidonic acid metabolism via the cyclooxygenase pathway in most mast cells, is… Expand
1988
1988
U-46619, a stable "functional" thromboxane/endoperoxide receptor agonist, produced potent contractile responses in isolated… Expand
1985
1985
1 Strips of rabbit blood vessels were suspended in vitro and responses to complement peptides C3a and C5a were recorded… Expand
1985
1985
Using [3H]leukotriene C4 (LTC4) and radioligand-binding techniques, specific leukotriene C4 binding sites have been identified in… Expand
1985
1985
[3H]Leukotriene (LT) D4 was used to identify specific LTD4 binding sites in guinea-pig ventricular myocardial membranes. High… Expand
1984
1984
SK&F 88046, an imidodisulfamide initially reported as an end organ leukotriene (LT)D4 antagonist on guinea-pig lung parenchyma… Expand
1984
1984
A radioligand binding assay has been established to study leukotriene specific binding sites in the guinea pig and rabbit tissues… Expand
1984
1984
In the present study, we evaluated the properties of an imidodisulfamide derivative, compound SKF 88046, as an antagonist of the… Expand
1984
1984
SK&F 88046 preferentially antagonized the contractions elicited by the functional thromboxane (Tx) A2 mimics and structural… Expand