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SK&F 86002

Known as: SKF 86002, SKF86002 
National Institutes of Health

Papers overview

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2017
2017
Solvatochromism and linear solvation energy relationship of the kinase inhibitor SKF86002.
2006
2006
Low density lipoproteins inhibit the Na+/H+ antiport in human platelets via activation of p38MAP kinase.
2004
2004
IL-2 and IL-10 Production by Human CD4+T Cells Is Differentially Regulated by p38: Mode of Stimulation-Dependent Regulation of IL-2
Antigenic stimulation of T cells initiates a complex series of intracellular signaling pathways that target and activate… 
2003
2003
P38 MAPK: critical molecule in thrombin-induced NF-kappa B-dependent leukocyte recruitment.
Thrombin-stimulated endothelium synthesizes numerous adhesion molecules to recruit leukocytes; however, it is unknown which… 
1997
1997
Effects of SK&F 86002 on cytokine-stimulated IL6 production in cultured neonatal mouse calvaria and SaOS2 osteoblastic cells: the role of prostaglandins and other mechanisms of action.
The cytokine-suppressant anti-inflammatory drug (CSAID) SK&F 86002 inhibits bone resorption in vitro and this effect cannot be… 
1996
1996
Cytokine inhibition preserves renal hemodynamic function following mesangial cell immune injury.
BACKGROUND We assessed the effect of a cytokine inhibitor, compound SKF 86002 (a bicyclic imidazole), on changes in renal… 
1994
1994
Cytokine suppressive anti-inflammatory compounds inhibit bone resorption in vitro.
1989
1989
The pharmacology of arachidonic acid-induced rat PMN leukocyte infiltration
Arachidonic Acid (AA) injected into a hindpaw of Lewis rats produces high levels of tissue myeloperoxidase (MPO), a biochemical… 
1989
1989
Effect of SK&F 86002 on cytokine production by human monocytes
Human monocytes respond to a variety of stimuliin vitro by producing a number of physiologically important macromolecules… 
1987
1987
Arachidonic acid-induced inflammation: Inhibition by dual inhibitor of arachidonic acid metabolism, SK&F 86002
The antiinflammatory activity of the structurally novel dual inhibitor of arachidonic acid metabolism, SK&F 86002 was evaluated… 
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