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SIX6 gene

Known as: SIX6, SINE OCULIS HOMEOBOX, DROSOPHILA, HOMOLOG OF, 6, SIX homeobox 6 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Identification and characterization of variants and a novel 4 bp deletion in the regulatory region of SIX6, a risk factor for primary open‐angle glaucoma
Primary open‐angle glaucoma (POAG) is a complex disease of multigenic inheritance and the most common subtype of glaucoma. SIX6… 
2017
2017
Association of SIX1/SIX6 locus polymorphisms with regional circumpapillary retinal nerve fibre layer thickness: The Nagahama study
SIX1 and SIX6 are glaucoma susceptibility genes. Previous reports indicate that the single nucleotide polymorphism (SNP… 
2015
2015
Quantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent.
2015
2015
A common, protein-coding variant of SIX6 is associated with reduced retinal nerve fiber layer thickness
Review
2014
Review
2014
Association of common SIX6 polymorphisms with peripapillary retinal nerve fiber layer thickness: the Singapore Chinese Eye Study.
PURPOSE Recently the common SIX6 missense variant rs33912345 was found to be highly associated with glaucoma. The aim of this… 
2014
2014
Interstitial deletion 14q22.3‐q23.2: Genotype–phenotype correlation
The increasing use of molecular tools in genetic diagnosis has produced a surge in the detection of genomic imbalances. Among the… 
2011
2011
Novel mutation in TGA stop-codon of bovine SIX6 gene
As a transcriptional regulatory gene of the SIX family, SIX6 (also known as OPTX2, SIX9), probably affects pituitary development… 
2010
2010
Proper differentiation of photoreceptors and amacrine cells depends on a regulatory loop between NeuroD and Six6
Timely generation of distinct neural cell types in appropriate numbers is fundamental for the generation of a functional retina… 
2009
2009
Regulation of a remote Sonic hedgehog forebrain enhancer by the Six 3 homeoprotein
The secreted morphogen, Sonic hedgehog (Shh) is a significant determinant of brain size and craniofacial morphology1–4. In humans… 
2001
2001
Exclusion of SIX6 hemizygosity in a child with anophthalmia, panhypopituitarism and renal failure.
We report a patient who presented with anophthalmia, panhypopituitarism, early onset of end stage renal failure, and craniofacial… 
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