SIRT7 gene

Known as: SIRT7, SIRTUIN 7, SIR2L7 
This gene plays a role in post-translational protein modification.
National Institutes of Health

Papers overview

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2016
2016
Although SIRT7 is a member of sirtuin family proteins that are described as NAD(+)-dependent class III histone deacetylases, the… (More)
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2015
2015
Metastasis is responsible for over 90% of cancer-associated mortality. In epithelial carcinomas, a key process in metastatic… (More)
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2014
2014
Sirtuins (SIRT1-7) have attracted considerable attention as regulators of metabolism over the past decade. However, the… (More)
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Highly Cited
2014
Highly Cited
2014
Mitochondrial activity is controlled by proteins encoded by both nuclear and mitochondrial DNA. Here, we identify Sirt7 as a… (More)
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Highly Cited
2012
Highly Cited
2012
Sirtuin proteins regulate diverse cellular pathways that influence genomic stability, metabolism and ageing. SIRT7 is a mammalian… (More)
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Highly Cited
2012
Highly Cited
2012
Among mammalian sirtuins, SIRT7 is the only enzyme residing in nucleoli where ribosomal DNA is transcribed. Recent reports… (More)
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Highly Cited
2009
Highly Cited
2009
Sirtuins, also designated class III histone deacetylases, are implicated in the regulation of cell division, apoptosis, DNA… (More)
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Highly Cited
2006
Highly Cited
2006
We investigated the role of SIRT7, one of the seven members of the mammalian sirtuin family. We show that SIRT7 is a widely… (More)
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Highly Cited
2005
Highly Cited
2005
Sir2 is a NAD+-dependent protein deacetylase that extends lifespan in yeast and worms. This study examines seven human proteins… (More)
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Highly Cited
2000
Highly Cited
2000
Sirtuins (Sir2-like proteins) are present in prokaryotes and eukaryotes. Here, two new human sirtuins (SIRT6 and SIRT7) are found… (More)
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