SIRT3 gene

Known as: SIRTUIN 3, SIR2L3, Sirtuin 3 Gene 
This gene plays a role in the regulation of protein acetylation.
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Functional defects in mitochondrial biology causally contribute to various human diseases, including cardiovascular disease… (More)
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2014
2014
Ischemia-reperfusion (IR) injury is significantly worse in aged hearts, but the underlying mechanisms are poorly understood. Age… (More)
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Highly Cited
2013
Highly Cited
2013
Progressive accumulation of defective mitochondria is a common feature of aged cells. SIRT3 is a NAD(+)-dependent protein… (More)
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Highly Cited
2013
Highly Cited
2013
Circadian clocks are self-sustained cellular oscillators that synchronize oxidative and reductive cycles in anticipation of the… (More)
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Highly Cited
2012
Highly Cited
2012
Mitochondrial protein hyperacetylation is a known consequence of sustained ethanol consumption and has been proposed to play a… (More)
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Review
2012
Review
2012
The sirtuins are a family of highly conserved NAD(+)-dependent deacetylases that act as cellular sensors to detect energy… (More)
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2011
2011
4-Hydroxynonenal (4-HNE) is an endogenous product of lipid peroxidation known to play a role in cellular signaling through… (More)
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Highly Cited
2009
Highly Cited
2009
SIRT3 is a member of the sirtuin family of NAD(+)-dependent deacetylases, which is localized to the mitochondria and is enriched… (More)
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Highly Cited
2008
Highly Cited
2008
Cellular longevity is a complex process relevant to age-related diseases including but not limited to chronic illness such as… (More)
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Highly Cited
2005
Highly Cited
2005
SIR2 genes control life span in model organisms, playing a central role in evolutionarily conserved pathways of aging and… (More)
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