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SIRT3 gene

Known as: SIRTUIN 3, SIR2L3, Sirtuin 3 Gene 
This gene plays a role in the regulation of protein acetylation.
National Institutes of Health

Related topics

Related topics

11 relations
DeacetylationHydrolysisNAD-Dependent Deacetylase Sirtuin-3, MitochondrialPost-Translational Protein Processing

Narrower (2)

SIRT3 wt AlleleSirtuin 3

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Allele-specific interaction between glutathione peroxidase 1 and manganese superoxide dismutase affects the levels of Bcl-2, Sirt3 and E-cadherin
Abstract Manganese superoxide dismutase (MnSOD) is a mitochondrial-resident enzyme that reduces superoxide to hydrogen peroxide… 
2017
2017
A Dual Agonist of Farnesoid X Receptor (FXR) and the G protein-coupled Receptor TGR5, INT-767, Slows Down Age-Related Kidney Disease in Mice
Even in healthy individuals, renal function gradually declines during aging. However, an observed variation in the rate of this… 
2017
2017
Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections
Sirtuin 3 (SIRT3) is the main mitochondrial deacetylase. SIRT3 regulates cell metabolism and redox homeostasis, and protects from… 
2016
2016
AGEs Decreased SIRT3 Expression and SIRT3 Activation Protected AGEs-Induced EPCs’ Dysfunction and Strengthened Anti-oxidant Capacity
Advanced glycation end products (AGEs) have been confirmed to induce dysfunction in endothelial progenitor cells (EPCs) and play… 
2016
2016
SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model
SIRT3 is a member of Sirtuins family, which belongs to NAD+ dependent class III histone deacetylases. Emerging evidence suggests… 
Review
2016
Review
2016
Roles of SIRT3 in heart failure: from bench to bedside
Heart failure (HF) represents the most common endpoint of most cardiovascular diseases (CVDs) which are the leading causes of… 
2016
2016
Deregulation of selective autophagy & sirtuin 3 expression in lung aging and pulmonary fibrosis
2014
2014
Manipulating mitochondria to treat disease
Parkinson’s disease (PD) is a neurological disorder caused by the degeneration of dopamine neurons in the brain. Current… 
2014
2014
Mono(2-ethylhexyl)phthalate accumulation disturbs energy metabolism of fat cells
Phthalates are lipophilic and tend to accumulate in adipose tissue, an important regulator of energy balance and glucose… 
2013
2013
Peek Metabolism in Mice Cycle Drives Mitochondrial Oxidative + Circadian Clock NAD
, (2013); 342 Science et al. Clara Bien Peek Metabolism in Mice Cycle Drives Mitochondrial Oxidative + Circadian Clock NAD This… 
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