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SIRT3 gene

Known as: SIRTUIN 3, SIR2L3, Sirtuin 3 Gene 
This gene plays a role in the regulation of protein acetylation.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Acute kidney injury (AKI) is a public health concern with an annual mortality rate that exceeds those of breast and prostate… Expand
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Highly Cited
2013
Highly Cited
2013
Progressive accumulation of defective mitochondria is a common feature of aged cells. SIRT3 is a NAD(+)-dependent protein… Expand
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Highly Cited
2013
Highly Cited
2013
Introduction The circadian clock is a transcriptional oscillator that is thought to couple internal energetic processes with the… Expand
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Highly Cited
2013
Highly Cited
2013
Background: Reversible lysine acetylation regulates the fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase (LCAD… Expand
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Review
2012
Review
2012
The sirtuins are a family of highly conserved NAD(+)-dependent deacetylases that act as cellular sensors to detect energy… Expand
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Highly Cited
2012
Highly Cited
2012
  • J. Fu, J. Jin, +9 authors W. Duan
  • The Journal of Biological Chemistry
  • 2012
  • Corpus ID: 37609030
Background: Mitochondrial dysfunction is a key event mediating mutant Htt-induced neurotoxicity. Results: trans-(−)-ϵ-Viniferin… Expand
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Highly Cited
2012
Highly Cited
2012
Mitochondrial protein hyperacetylation is a known consequence of sustained ethanol consumption and has been proposed to play a… Expand
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Highly Cited
2009
Highly Cited
2009
SIRT3 is a member of the sirtuin family of NAD+-dependent deacetylases, which is localized to the mitochondria and is enriched in… Expand
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Highly Cited
2008
Highly Cited
2008
Cellular longevity is a complex process relevant to age-related diseases including but not limited to chronic illness such as… Expand
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Highly Cited
2005
Highly Cited
2005
SIR2 genes control life span in model organisms, playing a central role in evolutionarily conserved pathways of aging and… Expand
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