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SIRT4 gene

Known as: SIRTUIN 4, SIR2L4, SIRT4 
National Institutes of Health

Related topics

Related topics

1 relation
SIRT3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
SIRT4 inhibits malignancy progression of NSCLCs, through mitochondrial dynamics mediated by the ERK-Drp1 pathway
SIRT4 is well-known for its deacetylase activity in energy metabolism, but little is known about its roles in carcinogenesis. We… 
Review
2016
Review
2016
The role of mitochondrial sirtuins in health and disease.
Highly Cited
2013
Highly Cited
2013
SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation
ABSTRACT Sirtuins are a family of protein deacetylases, deacylases, and ADP-ribosyltransferases that regulate life span, control… 
Highly Cited
2013
Highly Cited
2013
SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK
Efficient coupling of cellular energy production to metabolic demand is crucial to maintain organismal homeostasis. Here, we… 
Highly Cited
2013
Highly Cited
2013
SIRT4 Prevents Hypoxia-Induced Apoptosis in H9c2 Cardiomyoblast Cells
Aims: Apoptosis plays a critical role in cardiomyocyte loss during ischaemic heart injury. A detailed understanding of the… 
Highly Cited
2013
Highly Cited
2013
Glutamate dehydrogenase 1 and SIRT4 regulate glial development
Congenital hyperinsulinism/hyperammonemia (HI/HA) syndrome is caused by an activation mutation of glutamate dehydrogenase 1 (GDH1… 
Review
2012
Review
2012
Mitochondrial sirtuins and metabolic homeostasis.
2011
2011
The expression of Sirtuins 1 and 4 in peripheral blood leukocytes from patients with type 2 diabetes
This study was designed to investigate the relationship between SIRTs 1 and 4 in peripheral blood leukocytes (PBLs) and human… 
Highly Cited
2010
Highly Cited
2010
Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in rats.
The sirtuin proteins are nicotinamide adenine dinucleotide dependent deacetylases and adenosine diphosphate (ADP)-ribosyl… 
Highly Cited
2006
Highly Cited
2006
Insulin Secretion: SIRT4 Gets in on the Act
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