SIRT4 gene

Known as: SIRTUIN 4, SIR2L4, SIRT4 
 

Topic mentions per year

Topic mentions per year

2005-2017
051020052017

Papers overview

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2014
2014
Glutamine metabolism plays an essential role for growth and proliferation of many cancer cells by providing metabolites for the… (More)
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Highly Cited
2013
Highly Cited
2013
DNA damage elicits a cellular signaling response that initiates cell cycle arrest and DNA repair. Here, we find that DNA damage… (More)
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Highly Cited
2013
Highly Cited
2013
Lipid metabolism is tightly controlled by the nutritional state of the organism. Nutrient-rich conditions increase lipogenesis… (More)
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2013
2013
AIMS Apoptosis plays a critical role in cardiomyocyte loss during ischaemic heart injury. A detailed understanding of the… (More)
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2013
2013
Sirtuins are a family of protein deacetylases, deacylases, and ADP-ribosyltransferases that regulate life span, control the onset… (More)
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2010
Highly Cited
2010
SIRT4, a member of the sirtuin family, has been implicated in the regulation of insulin secretion by modulation of glutamate… (More)
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2009
2009
The sirtuins (SIRT1-7), also being referred to as class III HDACs, exert NAD-dependent deacetylase and/or ADP-ribosyltransferase… (More)
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Highly Cited
2007
Highly Cited
2007
Sirtuins are homologues of the yeast transcriptional repressor Sir2p and are conserved from bacteria to humans. We report that… (More)
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Highly Cited
2006
Highly Cited
2006
Sir2 is an NAD-dependent deacetylase that connects metabolism with longevity in yeast, flies, and worms. Mammals have seven Sir2… (More)
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Highly Cited
2005
Highly Cited
2005
Histone deacetylase inhibitors (HDIs) are a new class of drugs with significant antileukemic activity. To explore mechanisms of… (More)
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