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SIRT4 gene

Known as: SIRTUIN 4, SIR2L4, SIRT4 
 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Mitochondria play a critical role in energy production, cell signalling and cell survival. Defects in mitochondrial function… Expand
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Highly Cited
2013
Highly Cited
2013
DNA damage elicits a cellular signaling response that initiates cell cycle arrest and DNA repair. Here, we find that DNA damage… Expand
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Highly Cited
2013
Highly Cited
2013
Lipid metabolism is tightly controlled by the nutritional state of the organism. Nutrient-rich conditions increase lipogenesis… Expand
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Highly Cited
2013
Highly Cited
2013
Aims: Apoptosis plays a critical role in cardiomyocyte loss during ischaemic heart injury. A detailed understanding of the… Expand
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Highly Cited
2010
Highly Cited
2010
SIRT4, a member of the sirtuin family, has been implicated in the regulation of insulin secretion by modulation of glutamate… Expand
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Review
2010
Review
2010
Sirtuins are a highly conserved family of proteins whose activity can prolong the lifespan of model organisms such as yeast… Expand
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Highly Cited
2008
Highly Cited
2008
The enzymes of the Sirtuin family of nicotinamide-adenine-dinucleotide-dependent protein deacetylases are emerging key players in… Expand
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Highly Cited
2007
Highly Cited
2007
Sirtuins are homologues of the yeast transcriptional repressor Sir2p and are conserved from bacteria to humans. We report that… Expand
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Highly Cited
2006
Highly Cited
2006
Sir2 is an NAD-dependent deacetylase that connects metabolism with longevity in yeast, flies, and worms. Mammals have seven Sir2… Expand
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Highly Cited
2000
Highly Cited
2000
  • Roy A. Frye
  • Biochemical and biophysical research…
  • 2000
  • Corpus ID: 21028304
Sirtuins (Sir2-like proteins) are present in prokaryotes and eukaryotes. Here, two new human sirtuins (SIRT6 and SIRT7) are found… Expand
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