SHH gene

Known as: HHG1, TPT, SMMCI 
This gene is involved in signal transduction and neuronal development.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
The zone of polarizing activity (ZPA) in the posterior limb bud produces Sonic Hedgehog (Shh) protein, which plays a critical… (More)
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Embryonal tumours of the central nervous system (CNS) represent a heterogeneous group of tumours about which little is known… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The sequencing of the zebrafish genome should be completed by the end of 2002. Direct assignment of function on the basis of this… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The secreted factor Sonic hedgehog (SHH) is both required for and sufficient to induce multiple developmental processes… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling in vertebrates. The question remains unanswered… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Veratrum alkaloids and distal inhibitors of cholesterol biosynthesis have been studied for more than 30 years as potent… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Distinct classes of motor neurons and ventral interneurons are generated by the graded signaling activity of Sonic hedgehog (Shh… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The floor plate plays important roles in ventral pattern formation and axonal guidance within the neural tube of vertebrate… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Targeted gene disruption in the mouse shows that the Sonic hedgehog(Shh) gene plays a critical role in patterning of vertebrate… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Holoprosencephaly (HPE) is a common developmental defect of the forebrain and frequently the midface in humans, with both genetic… (More)
Is this relevant?