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SHH gene

Known as: HHG1, TPT, SMMCI 
This gene is involved in signal transduction and neuronal development.
National Institutes of Health

Related topics

Related topics

7 relations
Intercellular Communication ProcessPattern FormationSHH protein, humanSignal Transduction

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SHH wt Allele

Papers overview

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Highly Cited
2011
Highly Cited
2011
Dopaminergic neuronal differentiation protocol for human mesenchymal stem cells.
The generation of dopamine (DA) neurons from stem cells holds great promise for future biomedical research and in the clinical… 
Highly Cited
2007
Highly Cited
2007
Combined targeting of epidermal growth factor receptor and hedgehog signaling by gefitinib and cyclopamine cooperatively improves the cytotoxic effects of docetaxel on metastatic prostate cancer…
The epidermal growth factor receptor (EGFR) and hedgehog cascades provide a critical role in prostate cancer progression and… 
Highly Cited
2005
Highly Cited
2005
Single base pair change in the long‐range Sonic hedgehog limb‐specific enhancer is a genetic basis for preaxial polydactyly
In most instances of preaxial polydactyly (PPD), Sonic Hedgehog (Shh), an essential limb patterning signal, is ectopically… 
Highly Cited
2004
Highly Cited
2004
Hh pathway expression in human gut tissues and in inflammatory gut diseases
Sonic hedgehog (Shh) directs early gut patterning via epithelial–mesenchymal signaling and remains expressed in endoderm-derived… 
Highly Cited
2004
Highly Cited
2004
Reduced Thymocyte Development in Sonic Hedgehog Knockout Embryos 1
The Hedgehog family of secreted intercellular signaling molecules are regulators of patterning and organogenesis during animal… 
Highly Cited
2003
Highly Cited
2003
Wnt Regulation of Progenitor Maturation in the Cortex Depends on Shh or Fibroblast Growth Factor 2
In the embryonic mouse cerebral cortex, progenitors in the ventricular zone (VZ) undergo a developmental change between embryonic… 
Highly Cited
2003
Highly Cited
2003
Evidence for a second wave of oligodendrogenesis in the postnatal cerebral cortex of the mouse
The existing view is that cortical oligodendrocytes (OLs) in rodents are born from the cortical subventricular zone (SVZ) after… 
Highly Cited
2000
Highly Cited
2000
Retinoid signaling is required to complete the vertebrate cardiac left/right asymmetry pathway.
Vitamin A-deficient (VAD) quail embryos have severe abnormalities, including a high incidence of reversed cardiac situs. Using… 
Highly Cited
1999
Highly Cited
1999
Cholesterol Biosynthesis from Lanosterol
The cDNA encoding the 471-amino acid rat 7-dehydrocholesterol reductase (DHCR), an enzyme that has been implicated in both… 
Review
1990
Review
1990
Is blood pressure an important variable in research on aging and neuropsychological test performance?
Regression analyses using Blood Pressure, Age, and the multiplicative effect of Blood Pressure and Age as predictors of… 
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