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SHARPIN gene

Known as: SHANK-ASSOCIATED RH DOMAIN INTERACTOR, SHANK-Associated RH Domain Interactor Gene, SHANK-INTERACTING PROTEIN-LIKE 1 
This gene is involved in polyubiquitination.
National Institutes of Health

Related topics

Related topics

4 relations
ImmunoregulationPolyubiquitinationTumor Necrosis Factor Signaling Processsharpin

Papers overview

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Review
2018
Review
2018
SHANK 3 haploinsufficiency : a ” common ” but underdiagnosed highly penetrant monogenic cause of autism spectrum disorders
Autism spectrum disorders (ASD) are etiologically heterogeneous, with hundreds of rare, highly penetrant mutations and genomic… 
2017
2017
SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation
Estrogen receptor α is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. In our… 
2017
2017
The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex
ABSTRACT Sharpin, a multifunctional adaptor protein, regulates several signalling pathways. For example, Sharpin enhances signal… 
2017
2017
ENERGY AND AGROTECHNICAL INDICATORS IN THE TESTING OF MACHINE-TRACTOR UNITS WITH SUBSOILER
The present-day agriculture involves anthropogenic effects on the soil, including the compaction and overcompaction of soil… 
2015
2015
Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling
SHANK-associated RH domain interactor (SHARPIN) inhibits integrins through interaction with the integrin α-subunit. In addition… 
2011
2011
Loss-of-function of SHARPIN causes an osteopenic phenotype in mice
SHARPIN is a novel protein thought to interact with SHANK family and is widely expressed in multiple tissues/cells, including… 
2011
2011
SHARPIN regulates mitochondria-dependent apoptosis in keratinocytes.
2011
2011
SHARPIN Negatively Associates with TRAF2-Mediated NFκB Activation
NFκB is an inducible transcriptional factor controlled by two principal signaling cascades and plays pivotal roles in diverse… 
2009
2009
Mapping quantitative trait loci regulating chicken body composition traits.
Genome scans were conducted on an F(2) resource population derived from intercross of the White Plymouth Rock with the Silkies… 
2003
2003
Novel human and mouse genes encoding a shank‐interacting protein and its upregulation in gastric fundus of W/WV mouse
Background and Aims: A division of labor exists between different classes of interstitial cells of Cajal (ICC) in the… 
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