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SH2D1A gene

Known as: SIGNALING LYMPHOCYTE ACTIVATION MOLECULE-ASSOCIATED PROTEIN, SAP, SH2 DOMAIN PROTEIN 1A 
This gene plays roles in proliferation, differentiation and activation of B and T-cells.
National Institutes of Health

Related topics

Related topics

8 relations
B-Cell ActivationCell Cycle ControlMTCP1NB wt AlleleProtein p8 MTCP-1

Papers overview

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2018
2018
The relation of GH1, GHR and DGAT1 polymorphisms with estimated breeding values for milk production traits of German Holstein sires
We analysed the relations of estimated breeding values (EBV) of 315 German Holstein sires to their genotypes in growth hormone… 
2011
2011
Early and rapid detection of X‐linked lymphoproliferative syndrome with SH2D1A mutations by flow cytometry
X‐linked lymphoproliferative syndrome (XLP) is a rare immunodeficiency with extreme vulnerability to Epstein‐Barr virus (EBV… 
2006
2006
Lattice instability at phase transitions near the Lifshitz point in proper monoclinic ferroelectrics
The temperature dependence of acoustic properties of the Sn2P2(SexS1−x)6 uniaxial ferroelectric in the vicinity of the Lifshitz… 
Highly Cited
2005
Highly Cited
2005
Defective B cell responses in the absence of SH2D1A.
More than half of patients with X-linked lympho-proliferative disease, which is caused by a defect in the intracellular adapter… 
Highly Cited
2004
Highly Cited
2004
The adaptor protein SH2D1A regulates signaling through CD150 (SLAM) in B cells.
The CD150 receptor is expressed on activated T and B lymphocytes, dendritic cells, and monocytes. A TxYxxV/I motif in the CD150… 
Highly Cited
2002
Highly Cited
2002
Association of the X-linked Lymphoproliferative Disease Gene Product SAP/SH2D1A with 2B4, a Natural Killer Cell-activating Molecule, Is Dependent on Phosphoinositide 3-Kinase*
Natural killer (NK) cells express an activating receptor, 2B4, that enhances cellular cytotoxicity. Upon NK cell activation by… 
2000
2000
Structural basis for SH2D1A mutations in X-linked lymphoproliferative disease.
X-linked lymphoproliferative disease (XLP) is a rare and severe immune deficiency, characterized by abnormal immune responses to… 
1999
1999
SH2D1A mutation analysis for diagnosis of XLP in typical and atypical patients
Abstract. X-linked lymphoproliferative disease (XLP) is a rare inherited immunodeficiency to Epstein-Barr virus (EBV). The gene… 
1999
1999
The role of the Epstein-Barr virus in the oncogenesis of EBV(+) gastric carcinomas
Abstract Five hundred and thirteen cases of gastric carcinoma were investigated for the presence of viral RNA, and the clinico… 
Highly Cited
1976
Highly Cited
1976
Biological properties and viral surface antigens of Burkitt lymphoma- and mononucleosis- derived strains of Epstein-Barr virus released from transformed marmoset cells
Three strains of Epstein-Barr virus (EBV), two from Burkitt lymphoma (BL) and one from infectious mononucleosis (IM) were used to… 
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