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SGPP1 gene

Known as: SPPASE1, Sphingosine-1-Phosphate Phosphatase 1 Gene, SPP1 
This gene is involved in sphingosine-1-phosphate degradation.
National Institutes of Health

Papers overview

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2016
2016
Lysosome membrane permeabilization (LMP) mediates cell death in a variety of cancer cells. However, little is known about… Expand
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2016
2016
The bioactive sphingolipid sphingosine-1-phosphate (S1P) and the kinase that produces it have been implicated in inflammatory… Expand
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2016
2016
Aims/hypothesisIdentification of novel biomarkers for type 2 diabetes and their genetic determinants could lead to improved… Expand
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2015
2015
This study demonstrated that miR-21 and miR-95 expression were significantly higher in the ALDH1+CD133+subpopulation than in the… Expand
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2015
2015
Three genetic variants in the promoter of SPP1 (secreted phosphoprotein 1) gene have been reported to affect transcriptional… Expand
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Highly Cited
2014
Highly Cited
2014
The aberrant expression of microRNAs (miRNAs) is associated with colorectal carcinogenesis, but the underlying mechanisms are not… Expand
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Highly Cited
2013
Highly Cited
2013
Radiation resistance poses a major clinical challenge in cancer treatment, but little is known about how microRNA (miR) may… Expand
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2013
2013
Background: Sphingosine-1-phosphate phosphatase 1, encoded by Sgpp1, dephosphorylates the signaling lysophospholipid, S1P… Expand
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Highly Cited
2012
Highly Cited
2012
Phospho- and sphingolipids are crucial cellular and intracellular compounds. These lipids are required for active transport, a… Expand
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Highly Cited
2009
Highly Cited
2009
As the field of glycobiology grows, important roles for glycolipids and glycoproteins in neurological disorders are being… Expand
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