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SETD7 gene

Known as: KMT7, H3-K4-HMTase, KIAA1717 
This gene is involved in epigenetic control of gene expression.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Significance Protein methyltransferases constitute an emerging but undercharacterized class of therapeutic targets with diverse… Expand
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Highly Cited
2010
Highly Cited
2010
Posttranslational modifications of the RelA subunit of NF-kappaB, including acetylation and methylation, play a key role in… Expand
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Highly Cited
2009
Highly Cited
2009
Histone methylation and DNA methylation cooperatively regulate chromatin structure and gene activity. How these two systems… Expand
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Highly Cited
2009
Highly Cited
2009
Methylation of histone H4 lysine 20 (H4K20me) is essential for recruiting checkpoint proteins 53BP1/Crb2 to DNA lesions and… Expand
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2008
2008
The transcription factor ecotropic viral integration site 1 (Evi1) is associated with acute myeloid leukemia (AML) and… Expand
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Highly Cited
2004
Highly Cited
2004
Histone lysine methylation is a key regulator of gene expression and heterochromatin function, but little is known as to how this… Expand
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Highly Cited
2004
Highly Cited
2004
p53 is a tumour suppressor that regulates the cellular response to genotoxic stresses. p53 is a short-lived protein and its… Expand
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Highly Cited
2004
Highly Cited
2004
SET9 is a member of the SET domain-containing histone methyltransferase family that can specifically methylate histone 3 at… Expand
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Highly Cited
2002
Highly Cited
2002
A novel histone methyltransferase, termed Set9, was isolated from human cells. Set9 contains a SET domain, but lacks the pre- and… Expand
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Highly Cited
2001
Highly Cited
2001
Methylation of histone H3 at lysine 9 by SUV39H1 and subsequent recruitment of the heterochromatin protein HP1 has recently been… Expand
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