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SEPT5 wt Allele

Known as: CDCREL1, CDCREL-1, Peanut-Like 1 (Drosophila) Gene 
Human SEPT5 wild-type allele is located in the vicinity of 22q11.21 and is approximately 10 kb in length. This allele, which encodes septin-5 protein… Expand
National Institutes of Health

Related topics

Related topics

8 relations
22q11.21Cell Cycle ControlCytokinesisIntracellular Transport
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Broader (1)

SEPT5 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Phosphorylation of Adult Type Sept5 (CDCrel-1) by Cyclin-dependent Kinase 5 Inhibits Interaction with Syntaxin-1*
Increasing evidence implicates cyclin-dependent kinase 5 (Cdk5) in neuronal synaptic function. We searched for Cdk5 substrates in… Expand
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2007
2007
The role of Sept5 (CDCrel-1) phosphorylation by cyclin-dependent kinase 5 in the interaction with syntaxin-1
 
2005
2005
RING Finger Ubiquitin-Protein Isopeptide Ligase Nrdp1/FLRF Regulates Parkin Stability and Activity*
Parkin is a ubiquitin-protein isopeptide ligase. It has been suggested that loss of function in parkin causes accumulation and… Expand
Review
2004
Review
2004
[Etiology and pathogenesis of Parkinson's disease: from mitochondrial dysfunctions to familial Parkinson's disease].
  • N. Hattori
  • Rinsho shinkeigaku = Clinical neurology
  • 2004
    • Corpus ID: 38275575
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease. It is urgently needed to… Expand
Highly Cited
2003
Highly Cited
2003
Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1
Mutations in the parkin gene are linked to autosomal-recessive juvenile parkinsonism (AR-JP). Parkin functions as a ubiquitin… Expand
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Highly Cited
2002
Highly Cited
2002
The Septin CDCrel-1 Is Dispensable for Normal Development and Neurotransmitter Release
ABSTRACT Septins are GTPases required for the completion of cytokinesis in a variety of organisms, yet their role in this process… Expand
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2001
2001
Expression and analysis of properties of septin CDCrel-1 in exocytosis.
This chapter describes the expression and analysis of properties of septin CDCrel- 1 in exocytosis. For in vitro studies of… Expand
Highly Cited
2000
Highly Cited
2000
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1.
Parkinson's disease is a common neurodegenerative disorder in which familial-linked genes have provided novel insights into the… Expand
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Highly Cited
2000
Highly Cited
2000
Differential localization of septins in the mouse brain
We have carried out a comparative immunohistochemical study on four members of the septin family, CDCrel‐1, Septin6, CDC10, and… Expand
Highly Cited
1998
Highly Cited
1998
Localization of a novel septin protein, hCDCrel‐1, in neurons of human brain
SYNAPTIC function is critical for cell-cell communication and the characterization of proteins that function during vesicle… Expand
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