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- Influence
PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometry.
- B. Ma, K. Zhang, +4 authors G. Lajoie
- Chemistry, Medicine
- Rapid communications in mass spectrometry : RCM
- 30 October 2003
A number of different approaches have been described to identify proteins from tandem mass spectrometry (MS/MS) data. The most common approaches rely on the available databases to match experimental… Expand
PEAKS DB: De Novo Sequencing Assisted Database Search for Sensitive and Accurate Peptide Identification*
- J. Zhang, L. Xin, +7 authors B. Ma
- Computer Science, Medicine
- Molecular & Cellular Proteomics
- 20 December 2011
TLDR
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro
- S. Bendall, M. Stewart, +9 authors M. Bhatia
- Biology, Medicine
- Nature
- 30 August 2007
Distinctive properties of stem cells are not autonomously achieved, and recent evidence points to a level of external control from the microenvironment. Here, we demonstrate that self-renewal and… Expand
Matrigel: A complex protein mixture required for optimal growth of cell culture
- C. Hughes, L. Postovit, G. Lajoie
- Biology, Medicine
- Proteomics
- 1 May 2010
Numerous cell types require a surface for attachment to grow and proliferate. Certain cells, particularly primary and stem cells, necessitate the use of specialized growth matrices along with… Expand
Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus
- F. C. Beasley, Enrique D Vinés, +5 authors D. Heinrichs
- Biology, Medicine
- Molecular microbiology
- 1 May 2009
Iron is critical for virtually all forms of life. The production of high‐affinity iron chelators, siderophores, and the subsequent uptake of iron–siderophore complexes are a common strategy employed… Expand
The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ
- K. Pardee, X. Xu, +10 authors A. Edwards
- Biology, Medicine
- PLoS biology
- 1 February 2009
Heme is a ligand for the human nuclear receptors (NR) REV-ERBα and REV-ERBβ, which are transcriptional repressors that play important roles in circadian rhythm, lipid and glucose metabolism, and… Expand
PEAKS: Powerful Software for Peptide De Novo Sequencing by MS/MS
TLDR
- 76
- 11
Prevention of Amino Acid Conversion in SILAC Experiments with Embryonic Stem Cells *
- S. Bendall, Chris P. Hughes, M. Stewart, Brad Doble, M. Bhatia, G. Lajoie
- Biology, Medicine
- Molecular & Cellular Proteomics
- 1 September 2008
Recent studies using stable isotope labeling with amino acids in culture (SILAC) in quantitative proteomics have made mention of the problematic conversion of isotope-coded arginine to proline in… Expand
Integrating Structure, Bioinformatics, and Enzymology to Discover Function
- R. Sanishvili, A. Yakunin, +9 authors A. Edwards
- Biology, Medicine
- Journal of Biological Chemistry
- 11 July 2003
Structural proteomics projects are generating three-dimensional structures of novel, uncharacterized proteins at an increasing rate. However, structure alone is often insufficient to deduce the… Expand
Control of calcium oxalate crystal growth by face-specific adsorption of an osteopontin phosphopeptide.
- B. Grohe, Jason O'young, +5 authors G. Hunter
- Chemistry, Medicine
- Journal of the American Chemical Society
- 10 November 2007
Mineral-associated proteins have been proposed to regulate many aspects of biomineralization, including the location, type, orientation, shape, and texture of crystals. To understand how proteins… Expand