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SECTM1 protein, human

Known as: Protein K-12, secreted and transmembrane 1 protein, human, SECTM1 
Secreted and transmembrane protein 1 (248 aa, ~27 kDa) is encoded by the human SECTM1 gene. This protein may be involved in thymocyte signaling.
National Institutes of Health

Related topics

Related topics

8 relations
Extracellular SpaceGenes, RegulatorGolgi ApparatusImmune System Processes

Broader (1)

Membrane Proteins

Papers overview

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2020
2020
Molecular and genomic characterization of a novel equine molluscum contagiosum-like virus
Cases of pox-like lesions in horses and donkeys have been associated with poxviruses belonging to different genera of the family… 
2014
2014
Autocrine GM-CSF transcription in the leukemic progenitor cell line KG1a is mediated by the transcription factor ETS1 and is negatively regulated through SECTM1 mediated ligation of CD7.
2014
2014
Sa1805 An mTOR-Sirtuin Axis in the Intestinal Cell Differentiation Network
2014
2014
Sa1803 Dissecting the Oncogenic Activity of the Nuclear Receptor LRH-1 in the Colon
2014
2014
Sa1804 Dysregulation of WNT5A/ROR2 Signaling Pathway Characterizes the Progression of Barrett's-Associated Esophageal Adenocarcinoma
2013
2013
SECTM1 Produced by Tumor Cells Attracts Human Monocytes Via CD7-mediated Activation of the PI3K Pathway
Tumor-associated macrophages (TAMs) play essential roles in tumor progression and metastasis. Tumor cells recruit myeloid… 
2009
2009
Abstract A66: K12/SECTM1 promotes melanoma tumor progression via upregulation of integrin β3 expression
Metastatic melanoma is a leading cause of mortality in skin cancers with few therapeutic options. However, molecular mechanisms… 
2003
2003
KEY COMPARISON: CCQM-K12: The determination of creatinine in serum
2000
2000
Identification of CD7 as a Cognate of the Human K12 (SECTM1) Protein*
CD7 is a 40-kDa protein found primarily on T, NK, and pre-B cells; the function of the CD7 protein in the immune system is… 
1998
1998
Identification and characterization of K12 (SECTM1), a novel human gene that encodes a Golgi-associated protein with transmembrane and secreted isoforms.
The investigation of a DNase-hypersensitive site upstream of the CD7 gene on chromosome 17q25 has led to the discovery of a novel… 
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