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SEA 0400

Known as: 2-(4-((2,5-difluorophenyl)methoxy)phenoxy)-5-ethoxyaniline, SEA-0400, SEA0400 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Intracellular Ca2+ waves (CaWs) of cardiomyocytes are spontaneous events of Ca2+ release from the sarcoplasmic reticulum that are… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Long QT syndrome (LQTS) is associated with sudden cardiac death resulting from torsades de pointes (TdP), which are… Expand
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Highly Cited
2005
Highly Cited
2005
SEA0400 and KB-R7943 are compounds synthesised to block transsarcolemmal Na+/Ca2+ exchange current (INa/Ca); however, they Have… Expand
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Highly Cited
2004
Highly Cited
2004
Excessive salt intake is a major risk factor for hypertension. Here we identify the role of Na+/Ca2+ exchanger type 1 (NCX1) in… Expand
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Highly Cited
2004
Highly Cited
2004
SEA0400 is a potent and selective Na+/Ca2+ exchanger (NCX) inhibitor. We evaluated the inhibitory effects of SEA0400 on Na+i… Expand
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Review
2004
Review
2004
  • T. Iwamoto
  • Journal of pharmacological sciences
  • 2004
  • Corpus ID: 34881085
The Na+/Ca2+ exchanger (NCX) is an ion transporter that exchanges Na+ and Ca2+ in either Ca2+ efflux or Ca2+ influx mode… Expand
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Highly Cited
2003
Highly Cited
2003
The Na(+)/Ca(2+) exchanger (NCX) is involved in myocardial ischemia-reperfusion injuries. We examined the effects of 2-[4-[(2,5… Expand
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Highly Cited
2002
Highly Cited
2002
The effects of 2‐[4‐[(2,5‐difluorophenyl) methoxy]phenoxy]‐5‐ethoxyaniline (SEA0400), a newly synthesized Na+‐Ca2+ exchanger (NCX… Expand
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Highly Cited
2002
Highly Cited
2002
The role of the Na+-Ca2+ exchanger as a major determinant of cell Ca2+ is well defined in cardiac tissue, and there has been much… Expand
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Highly Cited
2001
Highly Cited
2001
The effect of the newly synthesized compound 2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline (SEA0400) on the Na+-Ca2… Expand
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