SCN8A gene

Known as: NaCh6, NAV1.6, sodium voltage-gated channel alpha subunit 8 
 
National Institutes of Health

Papers overview

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2015
2015
De novo mutations of the voltage-gated sodium channel gene SCN8A have recently been recognized as a cause of epileptic… (More)
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2014
2014
OBJECTIVE De novo SCN8A mutations have been reported in patients with epileptic encephalopathy. Herein we report seven patients… (More)
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2014
2014
Rare de novo mutations of sodium channels are thought to be an important cause of sporadic epilepsy. The well established role of… (More)
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2008
2008
The Scn8a gene encodes the alpha-subunit of Na(v)1.6, a neuronal voltage-gated sodium channel. Mice homozygous for mutations in… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The SCN8A gene on chromosome 12q13 encodes the voltage gated sodium channel Na(v)1.6, which is widely expressed in… (More)
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2000
2000
The sodium channel isoform NaCh6 is abundant in the adult rat brain and is expressed in both neurons and glia (Schaller et al… (More)
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1998
1998
The voltage-gated sodium channel SCN8A is associated with inherited neurological disorders in the mouse that include ataxia… (More)
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Highly Cited
1997
Highly Cited
1997
The voltage-gated sodium channel alpha subunit SCN8A is one of the most abundant sodium channels in neurons from brain and spinal… (More)
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Highly Cited
1996
Highly Cited
1996
Analysis of a transgene-induced mutation at the mouse med locus led to the identification of the novel voltage-gated sodium… (More)
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Highly Cited
1995
Highly Cited
1995
The mouse neurological mutant ‘motor endplate disease’ (med) is characterized by early onset progressive paralysis of the hind… (More)
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