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SCH 442416

Known as: 5-amino-7-(3-(4-methoxyphenyl)propyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine, SCH-442416, SCH442416 
National Institutes of Health

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2 relations

Broader (2)

PyrazolesPyrimidines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Correlation of transient adenosine release and oxygen changes in the caudate‐putamen
Adenosine is an endogenous nucleoside that modulates important physiological processes, such as vasodilation, in the central… 
2017
2017
Preclinical Evaluation and Quantification of 18F-Fluoroethyl and 18F-Fluoropropyl Analogs of SCH442416 as Radioligands for PET Imaging of the Adenosine A2A Receptor in Rat Brain
The cerebral adenosine A2A receptor is an attractive therapeutic target for neuropsychiatric disorders. 18F-fluoroethyl and 18F… 
2017
2017
Adenosine A2A Receptor Modulates the Activity of Globus Pallidus Neurons in Rats
The globus pallidus is a central nucleus in the basal ganglia motor control circuit. Morphological studies have revealed the… 
2015
2015
Effect of adenosine on GLAST expression in the retina of a chronic ocular hypertension rat model.
This study was performed to evaluate the effect of adenosine and an adenosine receptor antagonist on the expression of the L… 
2014
2014
An in vivo positron emission tomography study of adenosine 2A receptor occupancy by preladenant using 11C-SCH442416 in healthy hubjects.
Background: This PET study was conducted to investigate the receptor occupancy of 11C-SCH442416 in the human brain and to… 
2014
2014
Quantitative in vivo imaging of adenosine A2A receptors in the human brain using 11C-SCH442416 PET: a pilot study.
11C-SCH442416 was reported in preclinical studies with rodents and primates to be the first nonxanthine radioligand suitable for… 
2013
2013
Evaluation of the adenosine A2A receptor ligand [11C] SCH442416 in the rodent brain
2012
2012
Effect of A(2A) receptor antagonist (SCH 442416) on the mRNA expression of glutamate aspartate transporter and glutamine synthetase in rat retinal Müller cells under hypoxic conditions in vitro.
The purpose of the present study was to investigate the effect of the A(2A) receptor antagonist (SCH 442416) on the mRNA… 
2011
2011
Functional changes in postsynaptic adenosine A2A receptors during early stages of a rat model of Huntington disease
2011
2011
In vitro effect of adenosine A2A receptor antagonist SCH 442416 on the expression of glutamine synthetase and glutamate aspartate transporter in rat retinal Müller cells at elevated hydrostatic…
The aim of this study was to investigate the effect of an adenosine A2A receptor antagonist on the expression of… 
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