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Chronic administration of potassium canrenoate (SC-14266), a water-soluble anti-aldosterone agent, increased serum LH levels in… Expand 1. A competitive "mineralocorticoid" receptor-binding technique has been used to study plasma "mineralocoroticoid" activity in… Expand Chronic experiments were carried out on three groups of rats to evaluate tissue and electrolyte effects of a mineralocorticoid… Expand 1. Necturus maculosus kidney function has been examined using standard clearance techniques and renal tubular micropuncture… Expand Potassium prorenoate (SC-23992) is a water-soluble steroidal compound with the ability to antagonize the sodium-retaining and… Expand Histone acetylation in the kidney of the adrenalectomized rat was increased 5 min after a physiological dose of aldosterone. The… Expand Histone acetylation in the kidney of the adrenalectomized rat was increased 5 min after a physiological dose of aldosterone. The… Expand The metabolism of intravenously administered radioactive potassium canrenoate (SC-14266-3H) was studied in three men. Within 5… Expand This study was designed to examine the effect of adrenal steroid hormones on the response of the toad bladder to vasopressin… Expand