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SB-505124

Known as: SB505124 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
TGF-ß induces Lysyl hydroxylase 2b in human synovial osteoarthritic fibroblasts through ALK5 signaling
Lysyl hydroxylase 2b (LH2b) is known to increase pyridinoline cross-links, making collagen less susceptible to enzymatic… 
2012
2012
Cdk 4 / 6 Inhibition Induces Epithelial-Mesenchymal Transition and Enhances Invasiveness in Pancreatic Cancer Cells
2012
2012
Abstract 5222: A novel mechanism of microenvironment-mediated drug resistance in BRAF V600E melanoma with loss of PTEN
Despite recent success of the BRAF kinase inhibitor vemurafenib in the clinic, nearly all of those treated follow a course in… 
2012
2012
Therapeutic Discovery Cdk 4 / 6 Inhibition InducesEpithelial – MesenchymalTransition and Enhances Invasiveness in Pancreatic Cancer Cells
Aberrant activation of Cyclin D-Cdk4/6 signaling pathway is commonly found in pancreatic ductal adenocarcinoma (PDAC). Here, we… 
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