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SB 269970

Known as: 3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol, SB-269970 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
A wide body of evidence suggests that 5-HT7 receptors are implicated in a variety of central nervous system functions, including… Expand
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Highly Cited
2008
Highly Cited
2008
It has been established that serotonergic pathways project to cerebral areas involved in learning and memory and that serotonin… Expand
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Highly Cited
2008
Highly Cited
2008
5-HT7 receptors have been linked to a number of psychiatric disorders including anxiety and depression. The localization of 5-HT7… Expand
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Highly Cited
2007
Highly Cited
2007
Evidence has accumulated supporting a role for 5-hydroxytryptamine (5-HT)7 receptors in circadian rhythms, sleep, and mood… Expand
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Highly Cited
2006
Highly Cited
2006
The aim of the present study was to examine the effect of the selective 5-HT7 receptor antagonist SB 269970 (0.25-20 mg/kg) in… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The 5-hydroxytryptamine7 receptor (5-HT7) is implicated in circadian rhythm phase resetting, and 5-HT7 receptor… Expand
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Highly Cited
2004
Highly Cited
2004
  • A. Meneses
  • Behavioural Brain Research
  • 2004
  • Corpus ID: 7703168
There is an important debate regarding the functional role of the 5-HT(1A) and 5-HT(7) receptor in memory systems. Hence, the… Expand
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2004
2004
Recombinant 5-hydroxytryptamine 5-HT7 receptors are known to express constitutive, i.e., agonist-independent activity… Expand
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Highly Cited
2004
Highly Cited
2004
Studies using selective drugs and knockout mice have demonstrated that the 5-HT(7) receptor plays an instrumental role in… Expand
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Highly Cited
2000
Highly Cited
2000
The novel 5-HT(7) receptor antagonist, SB-269970-A, potently displaced [(3)H]-5-CT from human 5-HT(7(a)) (pK(i) 8.9+/-0.1) and 5… Expand
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