SB 269970

Known as: 3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol, SB-269970 
 

Topic mentions per year

Topic mentions per year

2000-2018
05101520002018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
A wide body of evidence suggests that 5-HT7 receptors are implicated in a variety of central nervous system functions, including… (More)
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2012
2012
The 5-hydroxytryptamine7 (5-HT7) receptor is a G-protein coupled receptor for serotonin that has been implicated in the… (More)
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2011
2011
Current antidepressants still display unsatisfactory efficacy and a delayed onset of therapeutic action. Here we show that the… (More)
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2008
2008
It has been established that serotonergic pathways project to cerebral areas involved in learning and memory and that serotonin… (More)
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2008
2008
5-HT7 receptors have been linked to a number of psychiatric disorders including anxiety and depression. The localization of 5-HT7… (More)
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2006
2006
The physiological function of 5-HT(7) receptors is not yet fully determined. This study was designed to characterize the… (More)
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2004
2004
There is an important debate regarding the functional role of the 5-HT(1A) and 5-HT(7) receptor in memory systems. Hence, the… (More)
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2004
2004
Recombinant 5-hydroxytryptamine 5-HT7 receptors are known to express constitutive, i.e., agonist-independent activity… (More)
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2001
2001
1. The presence of 5-HT(7) receptor mRNA and protein in 5-HT neurons suggests that this receptor may act as a 5-HT autoreceptor… (More)
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Highly Cited
2000
Highly Cited
2000
The novel 5-HT(7) receptor antagonist, SB-269970-A, potently displaced [(3)H]-5-CT from human 5-HT(7(a)) (pK(i) 8.9+/-0.1) and 5… (More)
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