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SB 242084

Known as: SB-242084, SB242084 
National Institutes of Health

Papers overview

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2013
2013
Serotonin 2C receptor antagonism ameliorates novelty-induced hypophagia in aged mice
2011
2011
5-HT2C receptor regulation of defensive responses in the rat dorsal periaqueductal gray
2010
2010
Genetic and pharmacological evidence that 5-HT2C receptor activation, but not inhibition, affects motivation to feed under a progressive ratio schedule of reinforcement
2009
2009
The effects of the selective 5-HT2C receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats
RationaleRats exposed to an uncontrollable stressor demonstrate a constellation of behaviors such as exaggerated freezing and… 
Highly Cited
2006
Highly Cited
2006
The effects of the 5-HT2C receptor antagonist SB242084 on locomotor activity induced by selective, or mixed, indirect serotonergic and dopaminergic agonists
RationaleThe 5-HT2C receptor modulates mesolimbic dopamine (DA) function and the expression of DA-dependent behaviors, including… 
2006
2006
SB 242084: A Selective 5‐HT2C Receptor Antagonist
SB 242084 is the most potent and selective 5-HT2C receptor antagonist thus far available. Thus, SB 242084 has high affinity for… 
2005
2005
Involvement of 5‐HT2C Receptors in the Regulation of Food Intake in Siberian Hamsters
The Siberian hamster provides a physiological model for understanding the hypothalamic control of energy metabolism as it… 
2004
2004
5-HT2 receptors differentially modulate dopamine-mediated auto-inhibition in A9 and A10 midbrain areas of the rat
Highly Cited
2003
Highly Cited
2003
5-HT2C receptors inhibit and 5-HT1A receptors activate the generation of spike–wave discharges in a genetic rat model of absence epilepsy
2001
2001
Serotonin, excitatory amino acids and the photic control of melatonin rhythms and SCN c-FOS in the rat
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