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SB 242084

Known as: SB-242084, SB242084 
 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Impulsive people have a strong urge to act without thinking. It is sometimes regarded as a positive trait but rash impulsiveness… Expand
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Highly Cited
2008
Highly Cited
2008
Serotonin (5-HT) is thought to play an important role in the regulation of behavioral inhibition. Studies manipulating 5-HT… Expand
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Highly Cited
2008
Highly Cited
2008
Previously, we showed that the 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration, and the ability of cocaine… Expand
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Highly Cited
2007
Highly Cited
2007
RationaleSerotonin (5-HT) has been linked to impulsivity with recent data suggesting that different receptor sub-types exert… Expand
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Highly Cited
2004
Highly Cited
2004
Anxiety-like behaviors are integral features of withdrawal from chronic ethanol exposure. In the experiments in the current study… Expand
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Highly Cited
2002
Highly Cited
2002
The 5-HT2C antagonist SB-242084 was examined in various anxiety tests at doses based on reversal of mCPP-induced hypoactivity (0… Expand
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Highly Cited
2001
Highly Cited
2001
The possible role of 5-HT1A and 5-HT2C receptors in the anxiety induced by fear, acute treatment with SSRI antidepressants or the… Expand
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Highly Cited
1999
Highly Cited
1999
Electrophysiological techniques and in vivo microdialysis were used to investigate the effect of SB 242084, a potent and… Expand
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Highly Cited
1998
Highly Cited
1998
The novel, preferential 5-HT2C receptor agonist, Ro 60-0175 ((S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine) (2.5 mg,kg… Expand
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Highly Cited
1997
Highly Cited
1997
SB 242084 has a high affinity (pKi 9.0) for the cloned human 5-HT2C receptor and 100- and 158-fold selectivity over the closely… Expand
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