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SAR1B gene

Known as: SAR1, S. CEREVISIAE, HOMOLOG B, SARA2, Secretion Associated, Ras Related GTPase 1B Gene 
This gene plays a role in vesicle transport.
National Institutes of Health

Related topics

Related topics

7 relations
GTP BindingHomo sapiensIntracellular TransportSAR1A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Baicalein Targets GTPase‐Mediated Autophagy to Eliminate Liver Tumor–Initiating Stem Cell–Like Cells Resistant to mTORC1 Inhibition
Drug resistance is a major problem in the treatment of liver cancer. Mammalian Target of Rapamycin 1 (mTORC1) inhibitors have… 
2018
2018
Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Nav1.5.
2018
2018
Dimeric sorting code for concentrative cargo selection by the COPII coat
Significance One-third of the mammalian genome encodes proteins that are transported by the secretory pathway. Coat protein… 
2017
2017
Understanding Chylomicron Retention Disease Through Sar1b Gtpase Gene Disruption: Insight From Cell Culture
Background— Understanding the specific mechanisms of rare autosomal disorders has greatly expanded insights into the complex… 
Review
2014
Review
2014
Update on Primary Hypobetalipoproteinemia
Abstract“Primary hypobetalipoproteinemia” refers to an eclectic group of inherited lipoprotein disorders characterized by low… 
2012
2012
Phosphorylation of Sar1b Protein Releases Liver Fatty Acid-binding Protein from Multiprotein Complex in Intestinal Cytosol Enabling It to Bind to Endoplasmic Reticulum (ER) and Bud the Pre…
Background: ATP is required to generate the pre-chylomicron transport vesicle from intestinal ER. Results: FABP1, part of a four… 
Highly Cited
2011
Highly Cited
2011
Molecular analysis and intestinal expression of SAR1 genes and proteins in Anderson's disease (Chylomicron retention disease)
BackgroundAnderson's disease (AD) or chylomicron retention disease (CMRD) is a very rare hereditary lipid malabsorption syndrome… 
2011
2011
Expression of Sar1b Enhances Chylomicron Assembly and Key Components of the Coat Protein Complex II System Driving Vesicle Budding
Objective—SAR1b plays a significant role in the assembly, organization, and function of the coat protein complex II, a critical… 
2011
2011
Anderson's disease/chylomicron retention disease in a Japanese patient with uniparental disomy 7 and a normal SAR1B gene protein coding sequence
BackgroundAnderson's Disease (AD)/Chylomicron Retention Disease (CMRD) is a rare hereditary hypocholesterolemic disorder… 
2008
2008
Marinesco‐Sjögren syndrome with atrophy of the brain stem tegmentum and dysplastic cytoarchitecture in the cerebral cortex
Marinesco‐Sjögren syndrome (MSS) is a progressive multisystem disease with autosomal recessive inheritance characterized by… 
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