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S12363

National Institutes of Health

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1 relation

Broader (1)

vinfosiltine

Papers overview

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2009
2009
Supramolecular organization of S12363-liposomes prepared with two different remote loading processes.
2008
2008
Consequences of ions and pH on the supramolecular organization of sphingomyelin and sphingomyelin/cholesterol bilayers.
2004
2004
Relationship between the cellular accumulation and the cytotoxicity of S12363, a new vinca alkaloid derivative
SummaryS 12363, a new vinca alkaloid derivative, was considerably more cytotoxic to murine L1210 cells and five human tumor cell… 
2004
2004
Phase II study of a new vinca alkaloid derivative, S12363, in advanced breast cancer
Vinca alkaloids are widely used in the medical treatment of breast cancer. Our study aimed to evaluate the therapeutic activity… 
1993
1993
Plasma pharmacokinetics of vinblastine and the investigational Vinca alkaloid N-(deacetyl-O-4-vinblastoyl-23)-L-ethyl isoleucinate in mice as determined by high-performance liquid chromatography.
The plasma pharmacokinetics of vinblastine and N-(deacetyl-O-4-vinblastoyl-23)-L-ethyl isoleucinate (VileE) in mice have been… 
1993
1993
Growth inhibitory activity of S12363, a novel vinca alkaloid derivative on human melanoma cell lines.
The growth inhibitory activity of S12363, a new antineoplastic agent which belongs to the vinca alkaloid group incorporating an… 
1993
1993
Evaluation of the time-schedule dependency for the cytotoxic activity of the new vinca alkaloid derivative, S 12363 (vinfosiltine).
1992
1992
Cardiostimulatory and antiarrhythmic activity of tubulin-binding agents.
Rhythmic, spontaneously pulsating cardiac cells cultured from newborn rats are immediately stimulated to beat faster by addition… 
1992
1992
Binding of a new vinca alkaloid derivative, S12363, to human plasma proteins and platelets. Usefulness of an erythrocyte partitioning technique
SummaryThe interactions of S12363 with human plasma proteins have been investigatedin vitro by an erythrocyte partitioning… 
1990
1990
Flow cytometric evaluation of the cell cycle perturbations induced by S12363, a new vinca alkaloid derivative.
L1210 cells treated for 21 hours with S12363, a new vinca alkaloid derivative and the parent compounds (vinblastine, vincristine… 
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