S12363

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2010
012319902010

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2009
2009
The S12363 anticancer drug was encapsulated into liposomes in an attempt to increase its therapeutic index. Loading of S12363 was… (More)
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2008
2008
For drug delivery purpose the anticancer drug S12363 was loaded into ESM/Chol-liposomes using either a pH or an ammonium gradient… (More)
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2006
2006
The plasma pharmacokinetics of vinblastine and A'-(deacetyl-O-4-vinblastoyl-23)-i.-ethyl isoleucinate (VileE) in mice have been… (More)
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1995
1995
Vinca alkaloids are widely used in the medical treatment of breast cancer. Our study aimed to evaluate the therapeutic activity… (More)
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1993
1993
The growth inhibitory activity of S12363, a new antineoplastic agent which belongs to the vinca alkaloid group incorporating an… (More)
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1993
1993
We conducted a phase II study with the new vinca alkaloid derivative S12363 in ten patients with metastatic malignant melanoma… (More)
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1992
1992
The interactions of S12363 with human plasma proteins have been investigatedin vitro by an erythrocyte partitioning technique… (More)
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1992
1992
Rhythmic, spontaneously pulsating cardiac cells cultured from newborn rats are immediately stimulated to beat faster by addition… (More)
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1992
1992
S 12363, a new vinca alkaloid derivative, was considerably more cytotoxic to murine L1210 cells and five human tumor cell lines… (More)
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1990
1990
L1210 cells treated for 21 hours with S12363, a new vinca alkaloid derivative and the parent compounds (vinblastine, vincristine… (More)
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