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Nitric oxide (NO) is a potential new therapeutic agent for sickle cell disease (SCD). We investigated the effects of NO donor on… Expand The aetiology of pre-eclampsia still eludes researchers. Recently, the development of laboratory techniques to measure the levels… Expand Nitric oxide (NO) is implicated in both secondary damage and recovery after traumatic brain injury (TBI). Transfer of NO groups… Expand The availability of nitric oxide (NO), which is required for the normal regulation of vascular tone, may be decreased in… Expand The lack of a simple assay for the quantification of S-nitrosothiols in complex biological matrices has hampered our… Expand OBJECTIVES
We investigated whether glutathione (GSH), a reduced thiol that modulates redox state and forms adducts of nitric… Expand 1 S‐nitrosoglutathione (GSNO) is a potent and selective anti‐platelet agent, despite the fact that its spontaneous rate of… Expand Earlier studies have shown that inhibition of aggregation of washed platelets (WP) by NO was enhanced almost 100-fold by H2O2. In… Expand The objective of this study was to identify a potential mechanism for S-nitrosation of proteins. Therefore, we assessed S… Expand Bovine serum albumin (albumin) was modified by treatment with nitric oxide (NO) to form S-nitrosoalbumin. Analysis of the reduced… Expand