S-Adenosylhomocysteine

Known as: (S)-5'-(S)-(3-Amino-3-carboxypropyl)-5'-thioadenosine, L-Homocysteine, S-(5'-deoxyadenosin-5'-yl)-, Adenosylhomocysteine, S 
An amino acid derivative and an intermediate in the synthesis of cysteine and adenosine. S-adenosylhomocysteine (SAH) is formed upon S… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
020040019472017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
BACKGROUND Autism is a complex neurodevelopmental disorder that usually presents in early childhood and that is thought to be… (More)
  • figure 1
  • table 1
  • table 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
p53 is a tumour suppressor that regulates the cellular response to genotoxic stresses. p53 is a short-lived protein and its… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND The pathogenic mechanism of homocysteine's effect on cardiovascular risk is poorly understood. Recent studies show… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Chronic nutritional deficiencies in folate, choline, methionine, vitamin B-6 and/or vitamin B-12 can perturb the complex… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Because S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) are the substrate and product of essential methyltransferase… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
S-Adenosylmethionine and S-adenosylhomocysteine (SAH), as the substrate and product of essential cellular methyltransferase… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Asymmetrical dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor. It is formed by protein arginine N… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 7
Is this relevant?
Highly Cited
2000
Highly Cited
2000
BACKGROUND The relative changes in plasma and intracellular concentrations of S-adenosylmethionine (SAM) and S… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
S-Adenosylmethionine is an essential ubiquitous metabolite central to many biochemical pathways, including transmethylation and… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
The crystal structure has been determined at 2.8 A resolution for a chemically-trapped covalent reaction intermediate between the… (More)
Is this relevant?