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S-Adenosylhomocysteine

Known as: (S)-5'-(S)-(3-Amino-3-carboxypropyl)-5'-thioadenosine, L-Homocysteine, S-(5'-deoxyadenosin-5'-yl)-, Adenosylhomocysteine, S 
An amino acid derivative and an intermediate in the synthesis of cysteine and adenosine. S-adenosylhomocysteine (SAH) is formed upon S… 
National Institutes of Health

Related topics

Related topics

10 relations
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (3)

S-(3-deazaadenosyl)homocysteineS-adenosyl-3-thiopropylamineS-tubercidinylhomocysteine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Methylthioadenosine/S‐adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism
The importance of methylthioadenosine/S‐adenosylhomocysteine (MTA/SAH) nucleosidase in bacteria has started to be appreciated… 
Review
2007
Review
2007
Metabolic regulatory properties of S-adenosylmethionine and S-adenosylhomocysteine
Abstract In mammalian liver, two intersecting pathways, remethylation and transsulfuration, compete for homocysteine that has… 
Highly Cited
2006
Highly Cited
2006
Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations.
Progressive ischaemic damage in animals is associated with spreading mass depolarizations of neurons and astrocytes, detected as… 
Highly Cited
2005
Highly Cited
2005
Mechanisms for the Inhibition of DNA Methyltransferases by Tea Catechins and Bioflavonoids
In the present investigation, we studied the modulating effects of several tea catechins and bioflavonoids on DNA methylation… 
Highly Cited
2004
Highly Cited
2004
S-adenosylhomocysteine hydrolase deficiency in a human: A genetic disorder of methionine metabolism
We report studies of a Croatian boy, a proven case of human S-adenosylhomocysteine (AdoHcy) hydrolase deficiency. Psychomotor… 
Review
2004
Review
2004
Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine.
Tissue concentrations of both homocysteine (Hcy) and cysteine (Cys) are maintained at low levels by regulated production and… 
Highly Cited
2003
Highly Cited
2003
Increased homocysteine and S-adenosylhomocysteine concentrations and DNA hypomethylation in vascular disease.
BACKGROUND The pathogenic mechanism of homocysteine's effect on cardiovascular risk is poorly understood. Recent studies show… 
Highly Cited
2002
Highly Cited
2002
Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology.
Chronic nutritional deficiencies in folate, choline, methionine, vitamin B-6 and/or vitamin B-12 can perturb the complex… 
Review
1996
Review
1996
S‐Adenosylmetliionine and methylation
S‐Adenosylmethionine (AdoMet or SAM) plays a pivotal role as a methyl donor in a myriad of biological and biochemical events… 
Highly Cited
1959
Highly Cited
1959
The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine.
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