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S 33138

Known as: S-33138, S33138 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Investigational dopamine antagonists for the treatment of schizophrenia
ABSTRACT Introduction: Schizophrenia is a debilitating illness with a chronic impact on social function and daily living… 
2012
2012
Pharmacological or genetic blockade of the dopamine D3 receptor increases cell proliferation in the hippocampus of adult mice
Dopamine plays an important role in cellular processes controlling the functional and structural plasticity of neurons, as well… 
2012
2012
Pharmacological and Genetic Modulation of Adult Neurogenesis in Animal Models Relevant to Neuropsychiatric Disorders
During the past decade, the modulation of adult neurogenesis has been an intensively studied area of neuroscience due to the… 
2011
2011
Development of a Complex Parent-Metabolite Joint Population Pharmacokinetic Model
This study aimed to develop a joint population pharmacokinetic model for an antipsychotic agent in development (S33138) and its… 
Highly Cited
2010
Highly Cited
2010
The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures.
Although dopamine D(3) receptor antagonists have been shown to enhance frontocortical cholinergic transmission and improve… 
Highly Cited
2009
Highly Cited
2009
The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats
Highly Cited
2008
Highly Cited
2008
S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], A Preferential Dopamine D3 versus D2 Receptor Antagonist and Potential…
The novel, potential antipsychotic, S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]benzopyrano[3,4-c]pyrrol-2(3H)-yl… 
Highly Cited
2008
Highly Cited
2008
S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1] benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenyl-acetamide), a Preferential Dopamine D3 versus D2 Receptor Antagonist and Potential…
In contrast to clinically available antipsychotics, the novel benzopyranopyrrolidine derivative, S33138 (N-[4-[2-[(3aS,9bR)-8… 
Review
2008
Review
2008
Cognitive impairment in schizophrenia: a review of developmental and genetic models, and pro-cognitive profile of the optimised D(3) > D(2) antagonist, S33138.
In vivo animal models are indispensable both for clarifying the pathological bases of schizophrenia, and for evaluating the… 
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