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S 23906-1

Known as: S-23906-1, S23906-1, S239061 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Acronine
analogs & derivatives

Papers overview

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2013
2013
Protein recognition of the S 23906-1 – DNA adduct by nuclear proteins : direct involvement of glyceraldehyde-3-phosphate dehydrogenase ( GAPDH ) 1
In a view to develop new DNA alkylating antitumour drugs, evaluating the precise mechanism of action and the molecular/cellular… 
2006
2006
290 POSTER The cytotoxic activity of the monofunctionaol alkylator S23906 is mediated by generation of DNA double strand breaks that are repaired by homologous recombination in mammalian cells
2002
2002
Alkylation of guanine in DNA by S23906-1, a novel potent antitumor compound derived from the plant alkaloid acronycine.
The discovery of a new DNA-targeted antitumor agent is a challenging enterprise, and the elucidation of its mechanism of action… 
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