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S 0139

Known as: S-0139 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Caffeic AcidsEndothelin receptor antagonistOleanolic Acid
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Synergistic Effect of an Endothelin Type A Receptor Antagonist, S-0139, With rtPA on the Neuroprotection After Embolic Stroke
Background and Purpose— Using a model of embolic stroke, the present study tested the hypothesis that blockage of endothelin-1… 
2003
2003
Highly enhanced permeability of blood-brain barrier induced by repeated administration of endothelin-1 in dogs and rats.
The effects of intracisternal administration of endothelin-1 on blood-brain barrier permeability were examined in dogs and rats… 
Review
2002
Review
2002
S-0139 (Shionogi).
Shionogi and GlaxoSmithKline (GSK), as the joint venture company Shionogi-GlaxoSmithKline Pharmaceuticals LLC, are developing S… 
Highly Cited
2001
Highly Cited
2001
Protective Effect of Endothelin Type A Receptor Antagonist on Brain Edema and Injury After Transient Middle Cerebral Artery Occlusion in Rats
Background and Purpose— Recent evidence strongly suggests that endothelins (ETs) play an important role in the regulation of… 
2000
2000
Endothelin receptor subtype antagonist activity of S-0139 in various isolated rabbit and canine arteries.
1999
1999
Different roles of two types of endothelin receptors in partial ablation-induced chronic renal failure in rats.
1999
1999
Contribution of endothelin-1 to disruption of blood-brain barrier permeability in dogs
Abstract. We examined the effect of intracisternal application of endothelin-1 (ET-1) on the permeability of fluorescein into the… 
1999
1999
A preventive effect of a selective endothelin-A receptor antagonist, S-0139, on the erythropoietin-induced reduction of the renal cortical blood flow
Abstract We have confirmed that renal cortical blood flow (RCBF) is significantly decreased by recombinant human erythropoietin… 
1998
1998
Potential contribution of endothelin to renal abnormalities in glycerol-induced acute renal failure in rats.
We studied the possible participation of endothelin-1 (ET-1) in the pathogenesis of renal damage in glycerol-induced acute renal… 
Highly Cited
1996
Highly Cited
1996
ICAM-1 expression on cardiac myocytes and aortic endothelial cells via their specific endothelin receptor subtype.
Endothelin-1 (ET-1) and Endothelin-3 (ET-3) increased the expression of intercellular adhesion molecule-1 (ICAM-1) on rat… 
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