Roxithromycin

Known as: (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-d-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one, RXM, Roxithromycin [Chemical/Ingredient] 
Semisynthetic derivative of erythromycin. It is concentrated by human phagocytes and is bioactive intracellularly. While the drug is active against a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
02040608019862018

Papers overview

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Highly Cited
2003
Highly Cited
2003
This study investigates the oxidation of pharmaceuticals during conventional ozonation and advanced oxidation processes (AOPs… (More)
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Highly Cited
2001
Highly Cited
2001
Ribosomes, the site of protein synthesis, are a major target for natural and synthetic antibiotics. Detailed knowledge of… (More)
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Highly Cited
2000
Highly Cited
2000
The effect of four macrolide antibiotics (roxithromycin, clarithromycin, erythromycin, and azithromycin) on the generation of… (More)
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2000
2000
OBJECTIVE To investigate the transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin… (More)
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Highly Cited
1999
Highly Cited
1999
AIMS Mounting evidence suggests infection, specifically Chlamydia pneumoniae, plays a role in atherosclerosis. We tested whether… (More)
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Highly Cited
1999
Highly Cited
1999
The recent monitoring of drug residues in the aquatic environment has gained much interest as many pharmaceutical compounds can… (More)
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1998
1998
There are many published reports on the anti-inflammatory effects of macrolides, some dating back to the introduction of… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND There is serological evidence for an association between Chlamydia pneumoniae and coronary heart disease. We… (More)
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1997
1997
Increased airway responsiveness (AR) is frequently associated with bronchiectasis. Roxithromycin is a new semisynthetic macrolide… (More)
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Highly Cited
1987
Highly Cited
1987
The intracellular accumulation and subcellular distribution of 14C-labelled roxithromycin and erythromycin has been studied in… (More)
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