Rocuronium

Known as: 1-(17-(acetoyl)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)pyrrolidinium 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND AND OBJECTIVE Sugammadex, a modified gamma-cyclodextrin, is a selective relaxant-binding agent designed to reverse the… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Rocuronium in intubation doses provides similar intubation conditions as succinylcholine, but has a longer duration of… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Sugammadex (Org 25969), a novel, selective relaxant binding agent, was specifically designed to rapidly reverse… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Sugammadex rapidly reverses rocuronium-induced neuromuscular block. This study explored the dose-response relation of… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Sugammadex is a modified [gamma] cyclodextrin compound, which encapsulates rocuronium to provide for a rapid reversal… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The reversal of a deep neuromuscular blockade remains a significant clinical problem. Sugammadex, a modified gamma… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Sugammadex reverses the neuromuscular blocking effects of rocuronium by chemical encapsulation. The efficacy, safety… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Sugammadex (Org 25969) forms a complex with steroidal neuromuscular blocking agents, thereby reversing neuromuscular… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND The purpose of this study was to determine the changes in the plasma concentration of rocuronium and the reversal of… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Succinylcholine has been the agent of choice when clinical conditions require emergency airway protection during a… (More)
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