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Rimantadine Hydrochloride

Known as: Rimantadine Hydrochloride [Chemical/Ingredient], 1-(1-Aminoethyl)adamantane Hydrochloride, alpha-Methyl-1-adamantanemethylamine Hydrochloride 
The hydrochloride salt form of rimantadine, a cyclic amine and alpha-methyl derivative of amantadine with antiviral activity. Although the exact… 
National Institutes of Health

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Papers overview

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Review
2006
Review
2006
Amantadine and rimantadine for influenza A in adults.
BACKGROUND Amantadine hydrochloride and rimantadine hydrochloride have antiviral properties, but they are not widely used due to… 
Highly Cited
1994
Highly Cited
1994
Functional reconstitution in lipid vesicles of influenza virus M2 protein expressed by baculovirus: evidence for proton transfer activity.
The influenza virus M2 protein was expressed from a recombinant baculovirus in Spodoptera frugiperda Sf9 cells, purified and… 
Review
1987
Review
1987
Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections.
Amantadine and rimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. This… 
Highly Cited
1986
Highly Cited
1986
Oral rimantadine hydrochloride therapy of influenza A virus H3N2 subtype infection in adults
In a randomized, double-blind trial involving patients with uncomplicated influenza A H3N2 subtype virus infection, rimantadine… 
Highly Cited
1986
Highly Cited
1986
Effectiveness of rimantadine prophylaxis of children within families.
With recent studies suggesting that children are the main introducers of influenza infections into families, we conducted a… 
Highly Cited
1985
Highly Cited
1985
Comparative single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride in young and elderly adults
The single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride were compared in a randomized, two… 
Highly Cited
1984
Highly Cited
1984
Safety of prolonged administration of rimantadine hydrochloride in the prophylaxis of influenza A virus infections in nursing homes
We evaluated the safety of rimantadine hydrochloride (RH) prophylaxis in a double-blind, placebo-controlled trial in three… 
Highly Cited
1983
Highly Cited
1983
Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics
In a double-blind, placebo-controlled study, the comparative toxicities and blood concentrations of amantadine hydrochloride and… 
Highly Cited
1981
Highly Cited
1981
Comparative toxicity of amantadine hydrochloride and rimantadine hydrochloride in healthy adults
The relative toxicities of amantadine and rimantadine were compared in a double-blind, placebo-controlled study involving healthy… 
Highly Cited
1979
Highly Cited
1979
Inhibition of influenza virus uncoating by rimantadine hydrochloride
In freeze-thaw lysates of MDCK cells infected with 32P-labeled influenza virus A/WSN in the presence of added RNase, acid… 
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