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Rimantadine Hydrochloride

Known as: Rimantadine Hydrochloride [Chemical/Ingredient], 1-(1-Aminoethyl)adamantane Hydrochloride, alpha-Methyl-1-adamantanemethylamine Hydrochloride 
The hydrochloride salt form of rimantadine, a cyclic amine and alpha-methyl derivative of amantadine with antiviral activity. Although the exact… Expand
National Institutes of Health

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Drug AllergyPoisoning by rifamycinsRimantadine

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Flumadine

Papers overview

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Highly Cited
2000
Highly Cited
2000
Comparison of central nervous system adverse effects of amantadine and rimantadine used as sequential prophylaxis of influenza A in elderly nursing home patients.
BACKGROUND Amantadine hydrochloride and rimantadine hydrochloride are recommended by the Centers for Disease Control and… Expand
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Highly Cited
1994
Highly Cited
1994
Functional reconstitution in lipid vesicles of influenza virus M2 protein expressed by baculovirus: evidence for proton transfer activity.
The influenza virus M2 protein was expressed from a recombinant baculovirus in Spodoptera frugiperda Sf9 cells, purified and… Expand
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Highly Cited
1986
Highly Cited
1986
Effectiveness of rimantadine prophylaxis of children within families.
With recent studies suggesting that children are the main introducers of influenza infections into families, we conducted a… Expand
Highly Cited
1986
Highly Cited
1986
Oral rimantadine hydrochloride therapy of influenza A virus H3N2 subtype infection in adults.
In a randomized, double-blind trial involving patients with uncomplicated influenza A H3N2 subtype virus infection, rimantadine… Expand
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Highly Cited
1985
Highly Cited
1985
Comparative single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride in young and elderly adults
The single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride were compared in a randomized, two… Expand
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Highly Cited
1984
Highly Cited
1984
Safety of prolonged administration of rimantadine hydrochloride in the prophylaxis of influenza A virus infections in nursing homes.
We evaluated the safety of rimantadine hydrochloride (RH) prophylaxis in a double-blind, placebo-controlled trial in three… Expand
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Highly Cited
1983
Highly Cited
1983
Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics.
In a double-blind, placebo-controlled study, the comparative toxicities and blood concentrations of amantadine hydrochloride and… Expand
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Highly Cited
1981
Highly Cited
1981
Comparative toxicity of amantadine hydrochloride and rimantadine hydrochloride in healthy adults.
The relative toxicities of amantadine and rimantadine were compared in a double-blind, placebo-controlled study involving healthy… Expand
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Highly Cited
1980
Highly Cited
1980
Plaque inhibition assay for drug susceptibility testing of influenza viruses.
The relative antiviral activities of four drugs against contemporary strains of influenza A and B viruses were determined in… Expand
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Highly Cited
1979
Highly Cited
1979
Inhibition of influenza virus uncoating by rimantadine hydrochloride.
In freeze-thaw lysates of MDCK cells infected with 32P-labeled influenza virus A/WSN in the presence of added RNase, acid… Expand
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