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Rimantadine Hydrochloride

Known as: Rimantadine Hydrochloride [Chemical/Ingredient], 1-(1-Aminoethyl)adamantane Hydrochloride, alpha-Methyl-1-adamantanemethylamine Hydrochloride 
The hydrochloride salt form of rimantadine, a cyclic amine and alpha-methyl derivative of amantadine with antiviral activity. Although the exact… 
National Institutes of Health

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Papers overview

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2014
2014
Synthesis of Three Rimantadine Schiff Bases and Their Biological Effects on Serum Albumin
Three new rimantadine Schiff bases (RSBs) were prepared, and then the interaction of RSBs with bovine serum albumin (BSA) was… 
2008
2008
Determination of rimantadine in rat plasma by liquid chromatography/electrospray mass spectrometry and its application in a pharmacokinetic study.
2005
2005
Rimantadine hydrochloride blocks the second step of influenza virus uncoating
SummaryTwo steps of influenza virus A/WSN uncoating in MDCK cells are described. The products of the first step are cores which… 
2004
2004
Validation of a Capillary Zone Electrophoresis Method for Determination of Rimantadine Hydrochloride in Rimantadin100 Tablets and the Method Application to Dissolution Test Monitoring
A capillary zone electrophoretic method with indirect UV‐detection for determination of rimantadine, an antiviral drug against… 
Review
2004
Review
2004
Amantadine and rimantadine for preventing and treating influenza A in adults.
BACKGROUND Amantadine hydrochloride and rimantadine hydrochloride have antiviral properties, but these drugs are not widely used… 
1992
1992
Quantitation of the enantiomers of rimantadine and its hydroxylated metabolites in human plasma by gas chromatography/mass spectrometry.
A gas chromatographic/mass spectrometric procedure has been developed for the quantitation in human plasma of the enantiomers of… 
1988
1988
Multiple-dose pharmacokinetics of rimantadine in elderly adults
To assess the possible effect of aging on rimantadine hydrochloride pharmacokinetics, single- and multiple-dose kinetics were… 
Highly Cited
1984
Highly Cited
1984
Combined interferon-alpha 2, rimantadine hydrochloride, and ribavirin inhibition of influenza virus replication in vitro
Recombinant DNA-produced human interferon-alpha 2 inhibited the replication of influenza A and B viruses in primary rhesus monkey… 
1975
1975
Treatment of Influenza Infection of Mice by Using Rimantadine Hydrochlorides by the Aerosol and Intraperitoneal Routes
Rimantadine hydrochloride was administered for 4 days in a small-particle (95% < 6.5 μm) aerosol (8.8 mg/kg per day) or… 
1965
1965
Antiviral activity of alpha-methyl-1-adamantanemethylamine hydrochloride.
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