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Ribonucleotide Reductase Inhibitor

Any substance that inhibits ribonucleotide reductase, an enzyme that catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleotide… 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Head and neck squamous cell carcinomas (HNSCCs) are the sixth most common malignant neoplasm and more than 50% of patients… 
2006
2006
Ribonucleotide reductase (RR) is the enzyme that catalyses the rate‐limiting step in DNA synthesis, the production of… 
2005
2005
ABSTRACT RAD53 and MEC1 are essential Saccharomyces cerevisiae genes required for the DNA replication and DNA damage checkpoint… 
2004
2004
PurposeRibonucleotide reductase (RR) is the rate-limiting enzyme of de novo DNA synthesis and has been shown to be upregulated… 
2000
2000
Upon appropriate drug treatment, the human erythroleukemic K562 cells have been shown to produce hemoglobin and F‐cells. Fetal… 
1996
1996
The ribonucleotide reductase (RR) of herpes simplex virus type 1 (HSV-1) is an important virulence factor, being required for… 
1994
1994
Evaluation of pharmacologic agents that stimulate fetal hemoglobin production has been done mainly in baboons and macaques. We… 
Review
1993
Review
1993
Inhibitors of the ribonucleotide reductase of herpes simplex viruses (HSV) potentiate the activity of acyclovir in vitro and in… 
1993