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Ribonucleotide Reductase Inhibitor
Any substance that inhibits ribonucleotide reductase, an enzyme that catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleotide…
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National Institutes of Health
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Ribonucleotide Reductase Inhibitors [MoA]
Papers overview
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2017
2017
Regulation of Substrate Degradation and Cancer Metabolism by the Fbw7 Ubiquitin Ligase
Ryan J. Davis
2017
Corpus ID: 90282206
Regulation of Substrate Degradation and Cancer Metabolism by the Fbw7 Ubiquitin Ligase
2017
2017
NUC041: a Prodrug of the DNA Methyl Transferase Inhibitor (DNMTI) and Ribonucleotide Reductase Inhibitor NUC013
R. Daifuku
2017
Corpus ID: 90567128
NUC013 (5-aza-2′,2′-difluroro-deoxycytidine) is preclinically safer and more effective than decitabine (Pharmaceuticals 2017, 10…
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2009
2009
Post-translational modification of the ribonucleotide reductase inhibitor, Sml1, in response to DNA damage
Bethany L. Andreson
2009
Corpus ID: 85613206
2007
2007
Motexafin gadolinium - Apoptosis inducer, radiation enhancer, thioredoxin reductase inhibitor, ribonucleotide reductase inhibitor
P. Ortizdemontellano
,
J. Evans
2007
Corpus ID: 86727595
2001
2001
Purine Deoxynucleoside Salvage in Giardia ZumbZiu
Kenneth
,
Baumz
,
+4 authors
T. Spector
2001
Corpus ID: 9169688
Giardia lamblia is dependent on the salvage of preformed purines and pyrimidines, including deoxythymidine. Dependence on…
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1988
1988
Modification of the repair of potentially lethal damage in plateau-phase Chinese hamster cells by 2-chlorodeoxyadenosine.
K. Tanabe
,
W. Hiraoka
,
M. Kuwabara
,
A. Matsuda
,
T. Ueda
,
F. Sato
Journal of Radiation Research
1988
Corpus ID: 30789687
The ability of 2-chlorodeoxyadenosine, a ribonucleotide reductase inhibitor, to inhibit the repair of potentially lethal damage…
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1985
1985
Effects of nucleotide pool imbalances on the excision repair of ultraviolet-induced damage in the DNA of human diploid fibroblasts.
R. Snyder
Basic life sciences
1985
Corpus ID: 23945476
Recent studies in our laboratory and others have demonstrated that DNA polymerase inhibitors such as the ara nucleosides…
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