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Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor.
Severely elevated levels of total homocysteine (approximately millimolar) in the blood typify the childhood disease homocystinuria, whereas modest levels (tens of micromolar) are commonly found inExpand
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Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination.
The Src family of nonreceptor tyrosine kinases are important regulators of a variety of cellular processes, including cytoskeletal organization, cell-cell contact, and cell-matrix adhesion.Expand
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The nil Hecke ring and cohomology of G/P for a Kac-Moody group G.
Let G be the group with Borel subgroup B, associated to a Kac-Moody Lie algebra [unk] (with Weyl group W and Cartan subalgebra [unk]). Then H(*)(G/B) has, among others, four distinguished structuresExpand
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T-equivariant K-theory of generalized flag varieties.
Let G be a Kac-Moody group with Borel subgroup B and compact maximal torus T. Analogous to Kostant and Kumar [Kostant, B. & Kumar, S. (1986) Proc. Natl. Acad. Sci. USA 83, 1543-1545], we define aExpand
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Isoimmunization against human chorionic gonadotropin with conjugates of processed beta-subunit of the hormone and tetanus toxoid.
The immunogenicity of the conjugate prepared from "processed" beta-subunit of human chorionic gonadotropin (choriogonadotropin, HCG) and tetanus toxoid has been studied in animals and a humanExpand
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Long-Term Follow-Up after Pneumatic Dilation for Achalasia Cardia: Factors Associated with Treatment Failure and Recurrence
BACKGROUND:Though most patients with achalasia cardia (AC) respond to pneumatic dilation (PD), one-third experienced recurrence. Long-term follow-up studies on factors associated with variousExpand
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CD45 expression by bone marrow plasma cells in multiple myeloma: clinical and biological correlations
Multiple myeloma (MM) is characterized by accumulation of clonal plasma cells (PCs). CD45, a key regulator of antigen-mediated signaling and activation in lymphocytes, is present in early stages ofExpand
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Ubiquitin-mediated degradation of active Src tyrosine kinase.
Src family tyrosine kinases are involved in modulating various signal transduction pathways leading to the induction of DNA synthesis and cytoskeletal reorganization in response to cell-cell orExpand
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Prognostic value of bone marrow angiogenesis in patients with multiple myeloma undergoing high-dose therapy
Summary:Bone marrow (BM) angiogenesis is increased in multiple myeloma and is an important prognostic factor. However, prior studies were mainly done on patients receiving conventional chemotherapyExpand
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Thalidomide as initial therapy for early-stage myeloma
Patients with early-stage myeloma are typically observed without therapy until symptomatic disease occurs. However, they are at high risk of progression to symptomatic myeloma, with a median time toExpand
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